[HTML][HTML] Spheroids as a model for endometriotic lesions
The development and progression of endometriotic lesions are poorly understood, but
immune cell dysfunction and inflammation are closely associated with the pathophysiology …
immune cell dysfunction and inflammation are closely associated with the pathophysiology …
Three-dimensional biofabrication models of endometriosis and the endometriotic microenvironment
Endometriosis occurs when endometrial-like tissue grows outside the uterine cavity, leading
to pelvic pain, infertility, and increased risk of ovarian cancer. The present study describes …
to pelvic pain, infertility, and increased risk of ovarian cancer. The present study describes …
Collagen I triggers directional migration, invasion and matrix remodeling of stroma cells in a 3D spheroid model of endometriosis
A Stejskalová, V Fincke, M Nowak, Y Schmidt… - Scientific reports, 2021 - nature.com
Endometriosis is a painful gynecological condition characterized by ectopic growth of
endometrial cells. Little is known about its pathogenesis, which is partially due to a lack of …
endometrial cells. Little is known about its pathogenesis, which is partially due to a lack of …
Endometrial-peritoneal interactions during endometriotic lesion establishment
ML Hull, CR Escareno, JM Godsland, JR Doig… - The American journal of …, 2008 - Elsevier
The pathophysiology of endometriosis remains unclear but involves a complex interaction
between ectopic endometrium and host peritoneal tissues. We hypothesized that disruption …
between ectopic endometrium and host peritoneal tissues. We hypothesized that disruption …
[HTML][HTML] A novel mouse model of endometriosis mimics human phenotype and reveals insights into the inflammatory contribution of shed endometrium
E Greaves, FL Cousins, A Murray… - The American journal of …, 2014 - Elsevier
Endometriosis is an estrogen-dependent inflammatory disorder characterized by the
presence of endometrial tissue outside the uterine cavity. Patients experience chronic pelvic …
presence of endometrial tissue outside the uterine cavity. Patients experience chronic pelvic …
[HTML][HTML] In vitro modeling of endometriosis and endometriotic microenvironment–Challenges and recent advances
A Gołąbek-Grenda, A Olejnik - Cellular signalling, 2022 - Elsevier
Endometriosis is a chronic condition with high prevalence in reproductive age women,
defined as the growth of endometrial tissue outside the uterine cavity, most commonly on the …
defined as the growth of endometrial tissue outside the uterine cavity, most commonly on the …
Novel three-dimensional in vitro models of ovarian endometriosis
D Brueggmann, C Templeman… - Journal of ovarian …, 2014 - Springer
Background Endometriosis is characterized by the presence of functional endometrial tissue
outside of the uterine cavity. It affects 1 in 10 women of reproductive age. This chronic …
outside of the uterine cavity. It affects 1 in 10 women of reproductive age. This chronic …
Endometrial stromal and epithelial cells exhibit unique aberrant molecular defects in patients with endometriosis
PC Logan, P Yango, ND Tran - Reproductive Sciences, 2018 - journals.sagepub.com
Context: Endometriosis is a chronic inflammatory disease that causes pain and infertility in
women of reproductive age. Objective: To investigate the pathologic pathways in …
women of reproductive age. Objective: To investigate the pathologic pathways in …
[HTML][HTML] Cellular junction and mesenchymal factors delineate an endometriosis-specific response of endometrial stromal cells to the mesothelium
LL Lin, S Makwana, M Chen, CM Wang… - Molecular and Cellular …, 2022 - Elsevier
Endometriosis is a debilitating gynecologic disorder that affects∼ 10% of women of
reproductive age. Endometriosis is characterized by growth of endometriosis lesions within …
reproductive age. Endometriosis is characterized by growth of endometriosis lesions within …
Establishing 3D Endometrial Organoids from the Mouse Uterus
S Tang, SE Parks, Z Liao, DI Cope, SE Blutt… - JoVE (Journal of …, 2023 - jove.com
Endometrial tissue lines the inner cavity of the uterus and is under the cyclical control of
estrogen and progesterone. It is a tissue that is composed of luminal and glandular …
estrogen and progesterone. It is a tissue that is composed of luminal and glandular …