This study aims to evaluate the potency of cisplatin (Cispt)-loaded liposome (LCispt) and
PEGylated liposome (PLCispt) as therapeutic nanoformulations in the treatment of bladder …

Background: Drug delivery systems have demonstrated promising results to cross blood–
brain barrier (BBB) and deliver the loaded therapeutics to the brain tumor. This study aims to …

Cisplatin (CDDP) is one of the most effective and potent anticancer drugs used as first-line
chemotherapy against several solid tumors. However, the severe side effects and its …

Cisplatin (CDDP) is a very active and cytotoxic agent but causes severe side effects, namely
nephrotoxicity, which limits the therapy. The present study aimed to evaluate the acute …

Cisplatin, first (platinum) compound to be evolved as an anticancer agent, has found its
important place in cancer chemotherapy. However, the dose-dependent toxicities of …

Cisplatin is a chemotherapeutic agent used for treating various malignancies. The study
aimed to prepare pegylated liposomal cisplatin and evaluate its efficacy against human …

The anionic lipid DPPG is known to enhance the cellular uptake of liposomes by forming
phase boundaries of high fusogenic potentials in vesicular membranes. The focus of this …

Purpose Ovarian cancer is the most lethal gynecologic malignancy. The combination of
paclitaxel (PTX) and carboplatin (CBP) is the first-line remedy for clinical ovarian cancer …

Carboplatin is a chemotherapeutic agent used against various malignancies such as
ovarian carcinoma. The aim of this study is to improve the therapeutic efficacy of carboplatin …

Lipid-polymer hybrid nanoparticles (LPHNP) are delivery systems for controlled drug
delivery at tumor sites. The superior biocompatible properties of lipids and structural …