Acute skin exposure to ultraviolet light triggers neutrophil-mediated kidney inflammation
S Skopelja-Gardner, J Tai, X Sun… - Proceedings of the …, 2021 - National Acad Sciences
Photosensitivity to ultraviolet (UV) light affects up to∼ 80% of lupus patients. Sunlight
exposure can exacerbate local as well as systemic manifestations of lupus, including …
exposure can exacerbate local as well as systemic manifestations of lupus, including …
Earlier onset of neutrophil-mediated inflammation in the ultraviolet-exposed skin of mice deficient in myeloperoxidase and NADPH oxidase
J Komatsu, H Koyama, N Maeda, Y Aratani - Inflammation Research, 2006 - Springer
Objective and design This study examined the role of neutrophil-derived reactive oxygen
species (ROS) in neutrophil recruitment into ultraviolet B (UVB)-exposed skin of mice …
species (ROS) in neutrophil recruitment into ultraviolet B (UVB)-exposed skin of mice …
[HTML][HTML] Human and murine evidence for mechanisms driving autoimmune photosensitivity
SJ Wolf, SN Estadt, JE Gudjonsson… - Frontiers in …, 2018 - frontiersin.org
Ultraviolet (UV) light is an important environmental trigger for systemic lupus erythematosus
(SLE) patients, yet the mechanisms by which UV light impacts disease are not fully known …
(SLE) patients, yet the mechanisms by which UV light impacts disease are not fully known …
Photosensitivity in lupus erythematosus
A Kuhn, S Beissert - Autoimmunity, 2005 - Taylor & Francis
Lupus erythematosus (LE) is an autoimmune disease which can be triggered by
environmental factors such as solar irradiation. It has long been observed that especially …
environmental factors such as solar irradiation. It has long been observed that especially …
Ultraviolet B irradiation causes stimulator of interferon genes–dependent production of protective type I interferon in mouse skin by recruited inflammatory monocytes
C Sontheimer, D Liggitt, KB Elkon - Arthritis & Rheumatology, 2017 - Wiley Online Library
Objective Photosensitivity is common in patients with systemic lupus erythematosus,
although the mechanisms linking ultraviolet (UV) light to flares are not well understood. We …
although the mechanisms linking ultraviolet (UV) light to flares are not well understood. We …
Ultraviolet radiation–induced injury, chemokines, and leukocyte recruitment: an amplification cycle triggering cutaneous lupus erythematosus
S Meller, F Winterberg, M Gilliet, A Müller… - Arthritis & …, 2005 - Wiley Online Library
Objective To investigate the activation and recruitment pathways of relevant leukocyte
subsets during the initiation and amplification of cutaneous lupus erythematosus (LE) …
subsets during the initiation and amplification of cutaneous lupus erythematosus (LE) …
The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS dependent
S Skopelja-Gardner, J An, J Tai, L Tanaka, X Sun… - Scientific reports, 2020 - nature.com
Most systemic lupus erythematosus (SLE) patients are photosensitive and ultraviolet B light
(UVB) exposure worsens cutaneous disease and precipitates systemic flares of disease …
(UVB) exposure worsens cutaneous disease and precipitates systemic flares of disease …
Light, including ultraviolet
E Maverakis, Y Miyamura, MP Bowen, G Correa… - Journal of …, 2010 - Elsevier
Ultraviolet (UV) light is intricately linked to the functional status of the cutaneous immune
system. In susceptible individuals, UV radiation can ignite pathogenic inflammatory …
system. In susceptible individuals, UV radiation can ignite pathogenic inflammatory …
Neutrophils infiltrating ultraviolet B-irradiated normal human skin display high IL-10 expression
G Piskin, JD Bos, MBM Teunissen - Archives of dermatological research, 2005 - Springer
Exposure to an erythemal dose of ultraviolet B (UVB) is known to induce interleukin (IL-10)
expression in human skin. It is generally believed that this IL-10 is predominantly expressed …
expression in human skin. It is generally believed that this IL-10 is predominantly expressed …
Effects of ultraviolet exposure on the immune system
J Garssen, H van Loveren - Critical Reviews™ in Immunology, 2001 - dl.begellhouse.com
Depletion of stratospheric ozone and changes in lifestyle lead to an increased exposure to
ultraviolet (UV) wavebands, especially in the UVB region (280− 320 nm). Besides the …
ultraviolet (UV) wavebands, especially in the UVB region (280− 320 nm). Besides the …