The role of interleukin‐4 in ultraviolet B light‐induced immunosuppression

AA El‐Ghorr, M Norval - Immunology, 1997 - Wiley Online Library
Prolonged exposure to ultraviolet light (UV) is known to lead to premature skin ageing,
increased incidence of cataract and a high risk of developing skin cancers. UV‐B irradiation …

Photosensitivity and photoprotection in patients with lupus erythematosus

J Ahluwalia, A Marsch - Lupus, 2019 - journals.sagepub.com
Lupus erythematosus (LE) represents a spectrum of inflammatory autoimmune disease
comprising varying clinical entities ranging from primary cutaneous to systemic disease …

Ultraviolet radiation and chronic inflammation—Molecules and mechanisms involved in skin carcinogenesis: A narrative review

M Ciążyńska, I Olejniczak-Staruch… - Life, 2021 - mdpi.com
The process of skin carcinogenesis is still not fully understood. Both experimental and
epidemiological evidence indicate that chronic inflammation is one of the hallmarks of …

A cytokine cascade including prostaglandin E2, IL-4, and IL-10 is responsible for UV-induced systemic immune suppression

V Shreedhar, T Giese, VW Sung… - The Journal of …, 1998 - journals.aai.org
Even though all of the energy contained with the UV wavelengths of solar radiation is
absorbed within the epidermis and upper layers of the dermis, UV irradiation can suppress …

Histologic changes associated with ultraviolet A-induced erythema in normal human skin

BA Gilchrest, NA Soter, JLM Hawk, RM Barr… - Journal of the American …, 1983 - Elsevier
We have examined the effects of a standardized, moderately erythemogenic dose of long-
wave ultraviolet (UVA) radiation on normal human skin, with the use of an appropriately …

Comparative quantification of IL-1β, IL-10, IL-10r, TNFα and IL-7 mRNA levels in UV-irradiated human skin in vivo

N Brink, M Szamel, AR Young, KP Wittern… - Inflammation …, 2000 - Springer
Abstract Objective and Design: Ultraviolet (UV) exposure induces local immunosuppression
and inflammation in human skin. Cytokines are, in part, responsible for these responses. To …

Mechanisms involved in ultraviolet light‐induced immunosuppression

F Aubin - European journal of dermatology, 2003 - jle.com
Ultraviolet radiation (UV) represents one of the most important environmental factors
affecting human health, especially with regard to its hazardous effects on the generation of …

Impaired immunosuppressive response to ultraviolet radiation in interleukin-10–deficient mice

S Beissert, J Hosoi, R Kühn, K Rajewsky… - Journal of investigative …, 1996 - Elsevier
Exposure to mid-range ultraviolet radiation (UVR)[280–320 nm, ultraviolet B (UVB) radiation]
inhibits the acquisition of delayed-type hypersensitivity in mice and contact hypersensitivity …

Interleukin-12 prevents ultraviolet B-induced local immunosuppression and overcomes UVB-induced tolerance

A Schwarz, S Grabbe, Y Aragane, K Sandkuhl… - Journal of investigative …, 1996 - Elsevier
Ultraviolet (UV) light abrogates contact hypersensitivity (CHS) responses and induces
hapten-specific tolerance. Because Th-1 cells are critically involved in CHS and are induced …

Ultraviolet B irradiation-enhanced interleukin (IL)-6 production and mRNA expression are mediated by IL-1α in cultured human keratinocytes

JH Chung, SH Youn, WS Koh, HC Eun, KH Cho… - Journal of investigative …, 1996 - Elsevier
Ultraviolet (UV) B radiation may trigger cutaneous inflammatory responses by directly
inducing epidermal keratinocytes to elaborate specific cytokines such as interleukin (IL)-1 …