Microvesicles as risk markers for venous thrombosis

PE Rautou, N Mackman - Expert review of hematology, 2013 - Taylor & Francis
Microvesicles (MVs) are small (0.1–1 µm) membrane vesicles released from activated cells.
The surface of MVs can be highly procoagulant due to the presence of the procoagulant …

[HTML][HTML] Plasma levels of platelet‐derived microvesicles are associated with risk of future venous thromboembolism

O Snir, L Wilsgård, N Latysheva, CJE Wahlund… - Journal of Thrombosis …, 2022 - Elsevier
Abstract Background Microvesicles (MVs) are small double‐membrane encapsulated
particles shed from cells. Case‐control studies have reported elevated plasma levels of …

Microparticles as biomarkers of venous thromboembolic events

E Campello, L Spiezia, CM Radu… - Biomarkers in …, 2016 - Taylor & Francis
Microparticles (MPs) are small (0.1–1.0 μm) membrane vesicles constitutively released from
the surface of cells after activation and apoptosis. The clinical research on MPs is hampered …

Clinical significance of circulating microparticles for venous thrombo-embolism in cancer patients

J Thaler, C Ay, I Pabinger - Hämostaseologie, 2012 - thieme-connect.com
Cancer patients have a four-to seven-fold increased risk to develop a venous
thromboembolic event. Accumulating evidence from experimental and clinical studies …

[HTML][HTML] Tissue factor–positive tumor microvesicles activate platelets and enhance thrombosis in mice

JE Geddings, Y Hisada, Y Boulaftali, TM Getz… - Journal of thrombosis …, 2016 - Elsevier
Essentials• Cancer patients have a high rate of venous thrombosis (VT) but the underlying
mechanisms are unknown.• Tumor‐derived, tissue factor‐positive microvesicles in platelet …

Thrombin generation assay and transmission electron microscopy: a useful combination to study tissue factor-bearing microvesicles

D Gheldof, J Hardij, F Cecchet, B Chatelain… - Journal of …, 2013 - Taylor & Francis
Introduction. Patients with cancer have a 7-to 10-fold increased risk of developing venous
thromboembolism. Circulating microvesicles could be a useful predictive biomarker for …

Microvesicles and cancer associated thrombosis

R Lacroix, L Vallier, A Bonifay… - … in Thrombosis and …, 2019 - thieme-connect.com
Microvesicles (MVs) are small membrane enclosed structures released into the extracellular
space by virtually all cell types. Their composition varies according to the cell origin and the …

Endothelial, platelet, and tissue factor-bearing microparticles in cancer patients with and without venous thromboembolism

E Campello, L Spiezia, CM Radu, C Bulato… - Thrombosis research, 2011 - Elsevier
BACKGROUND: Cancer is a prothrombotic state, with an increased prevalence of venous
thromboembolism (VTE). Microparticles (MPs) are sub-micron-sized vesicles derived from …

[HTML][HTML] Methodology for isolation, identification and characterization of microvesicles in peripheral blood

M Jayachandran, VM Miller, JA Heit… - Journal of immunological …, 2012 - Elsevier
RATIONALE: Analyses of circulating cell membrane-derived microvesicles (MV) have come
under scrutiny as potential diagnostic and prognostic biomarkers of disease. However …

Membrane microvesicles: macromessengers in cancer disease and progression

D Castellana, F Toti, JM Freyssinet - Thrombosis research, 2010 - Elsevier
Thrombotic complications have been documented in patients with cancer, and associated
with tumor progression. Cancer patients have an increased level of circulating …