[HTML][HTML] Differential effects of class I antiarrhythmic drugs on the guinea pig pulmonary vein myocardium: Inhibition of automatic activity correlates with blockade of a …

M Irie, H Hiiro, S Kato, M Kuramochi… - Journal of …, 2020 - Elsevier
The effects of class I antiarrhythmic drugs on the automaticity of isolated guinea pig
pulmonary vein myocardia were investigated using microelectrode and voltage clamp …

[HTML][HTML] Involvement of the persistent Na+ current in the diastolic depolarization and automaticity of the guinea pig pulmonary vein myocardium

M Irie, H Hiiro, S Hamaguchi, I Namekata… - Journal of …, 2019 - Elsevier
The role of the Na+ current in the automaticity of the pulmonary vein myocardium was
examined in isolated guinea pig pulmonary vein cardiomyocytes and tissue preparations …

[HTML][HTML] Involvement of alpha-and beta-adrenoceptors in the automaticity of the isolated guinea pig pulmonary vein myocardium

M Irie, Y Tsuneoka, M Shimobayashi… - Journal of …, 2017 - Elsevier
We examined the involvement of adrenoceptors in the automaticity of the pulmonary vein
myocardium, which probably plays a crucial role in the generation of atrial fibrillation. The …

Inhibitory effect of a late sodium current blocker, NCC-3902, on the automaticity of the guinea pig pulmonary vein myocardium

I Namekata, H Hiiro, R Odaka, T Saito… - Biological and …, 2022 - jstage.jst.go.jp
The effect of blocking the persistent component of the sodium channel current (late I Na) on
the automatic activity of the isolated guinea pig pulmonary vein myocardium was examined …

[HTML][HTML] Permissive role of reduced inwardly-rectifying potassium current density in the automaticity of the guinea pig pulmonary vein myocardium

Y Tsuneoka, M Irie, Y Tanaka, T Sugimoto… - Journal of …, 2017 - Elsevier
The electrophysiological properties underlying the automaticity of the guinea pig pulmonary
vein myocardium were studied. About 30% of the isolated pulmonary vein tissue …

Electrophysiological effects of the antiarrhythmic drug bepridil on the guinea-pig pulmonary vein myocardium

A Takahara, K Takeda, M Hagiwara… - Biological and …, 2013 - jstage.jst.go.jp
We compared effects of the antiarrhythmic drug bepridil on the electrophysiological
parameters in the isolated pulmonary vein preparation from guinea pigs with those in the left …

THE EFFECTS OF QUINIDINE AND VERAPAMIL ON ELECTRICALLY INDUCED AUTOMATICITY IN THE VENTRICULAR MYOCARDIUM OF GUINEA PIG¹ 2

AO Grant, BG Katzung - Cardiovascular Effects of Verapamil, 1977 - books.google.com
ABSTRACT GRANT, AO AND BG KATZUNG: The effects of quinidine and verapamil on
electrically induced automaticity in the ventricular myocardium of guinea pig. J. Pharmacol …

Electrophysiological effects of the class Ic antiarrhythmic drug pilsicainide on the guinea-pig pulmonary vein myocardium

A Takahara, K Takeda, Y Tsuneoka, M Hagiwara… - Journal of …, 2012 - Elsevier
The pulmonary vein is known as an important source of ectopic beats, initiating frequent
paroxysms of atrial fibrillation. We compared effects of the class Ic antiarrhythmic drug …

Electrophysiological and pharmacological characteristics of triggered activity elicited in guinea-pig pulmonary vein myocardium

A Takahara, T Sugimoto, T Kitamura, K Takeda… - Journal of …, 2011 - Elsevier
The pulmonary vein is known as an important source of ectopic beats, initiating frequent
paroxysms of atrial fibrillation. We analyzed electrophysiological and pharmacological …

Electrophysiologic effects of nicainoprol, a putative class I antiarrhythmic agent, on the guinea pig ventricular papillary muscle

T Kimura, S Imanishi, M Arita - Journal of cardiovascular …, 1989 - journals.lww.com
We examined the effects of nicainoprol (1-50 [mu] M), a new antiarrhythmic agent, on the
transmembrane action potentials in isolated papillary muscles of the guinea pig. Nicainoprol …