[HTML][HTML] Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

KL Wyres, TNT Nguyen, MMC Lam, LM Judd… - Genome medicine, 2020 - Springer
Background Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI).
Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are …

[HTML][HTML] Large-scale genomic analysis of global Klebsiella pneumoniae plasmids reveals multiple simultaneous clusters of carbapenem-resistant hypervirulent …

A Spadar, J Perdigão, S Campino, TG Clark - Genome medicine, 2023 - Springer
Abstract Background Klebsiella pneumoniae (Kp) Gram-negative bacteria cause
nosocomial infections and rapidly acquire antimicrobial resistance (AMR), which makes it a …

[HTML][HTML] Genomic dissection of Klebsiella pneumoniae infections in hospital patients reveals insights into an opportunistic pathogen

CL Gorrie, M Mirčeta, RR Wick, LM Judd… - Nature …, 2022 - nature.com
Klebsiella pneumoniae is a major cause of opportunistic healthcare-associated infections,
which are increasingly complicated by the presence of extended-spectrum beta-lactamases …

Genomic surveillance framework and global population structure for Klebsiella pneumoniae

MMC Lam, RR Wick, SC Watts, LT Cerdeira, KL Wyres… - BioRxiv, 2020 - biorxiv.org
ABSTRACT K. pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-
associated infections, community-acquired liver abscess and urinary tract infections, and is …

[HTML][HTML] Genomic surveillance for multidrug-resistant or hypervirulent Klebsiella pneumoniae among United States bloodstream isolates

TJ Kochan, SH Nozick, RL Medernach… - BMC infectious …, 2022 - Springer
Background Klebsiella pneumoniae strains have been divided into two major categories:
classical K. pneumoniae, which are frequently multidrug-resistant and cause hospital …

[HTML][HTML] A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

MMC Lam, RR Wick, SC Watts, LT Cerdeira… - Nature …, 2021 - nature.com
Klebsiella pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-
associated infections, neonatal sepsis and community-acquired liver abscess, and is …

A high‐resolution genomic analysis of multidrug‐resistant hospital outbreaks of Klebsiella pneumoniae

H Chung The, A Karkey, D Pham Thanh… - EMBO molecular …, 2015 - embopress.org
Multidrug‐resistant (MDR) Klebsiella pneumoniae has become a leading cause of
nosocomial infections worldwide. Despite its prominence, little is known about the genetic …

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

KE Holt, H Wertheim, RN Zadoks… - Proceedings of the …, 2015 - National Acad Sciences
Klebsiella pneumoniae is now recognized as an urgent threat to human health because of
the emergence of multidrug-resistant strains associated with hospital outbreaks and …

Whole-genome sequencing of human clinical Klebsiella pneumoniae isolates reveals misidentification and misunderstandings of Klebsiella pneumoniae, Klebsiella …

SW Long, SE Linson, M Ojeda Saavedra, C Cantu… - Msphere, 2017 - Am Soc Microbiol
Klebsiella pneumoniae is a major threat to public health, causing significant morbidity and
mortality worldwide. The emergence of highly drug-resistant strains is particularly …

[HTML][HTML] Genomic definition of hypervirulent and multidrug-resistant Klebsiella pneumoniae clonal groups

S Bialek-Davenet, A Criscuolo, F Ailloud… - Emerging infectious …, 2014 - ncbi.nlm.nih.gov
Multidrug-resistant and highly virulent Klebsiella pneumoniae isolates are emerging, but the
clonal groups (CGs) corresponding to these high-risk strains have remained imprecisely …