Background Germline variant evaluation in precision oncology opens new paths toward the
identification of patients with genetic tumor risk syndromes and the exploration of therapeutic …

Hereditary cancer syndromes account for nearly 10% of cancers even though they are often
underdiagnosed. Finding a pathogenic gene variant could have dramatic implications in …

The purpose of this study was to obtain genetic counselors' perspectives about the
identification of appropriate patients and barriers to referral of high-risk patients for cancer …

Purpose Personalized information is paramount to patient-centered communication and
decision-making regarding risk management in hereditary cancer syndromes. This …

Objective: To increase the awareness among at risk relatives of the availability of genetic
testing for a familial disorder while respecting their autonomy and privacy. Methods: This …

Simple Summary Germline genetic testing for patients with cancer can have important
implications for treatment, preventive options, and for family members. In a mainstream …

Approximately 5% to 10% of cancers are attributable to a hereditary cancer predisposition
syndrome. Identifying those patients with cancer who have an inherited cancer …

Importance To promote the identification of women carryingBRCA1/2variants, the US
Preventive Services Task Force recommends that primary care clinicians screen …

Cascade testing for cancer predisposition offers a highly efficient and cost-effective method
for identifying individuals at increased risk for cancer, in whom targeted interventions can …

Background: Hereditary cancer panels (HCPs), testing for multiple genes and syndromes,
are rapidly transforming cancer risk assessment but are controversial and lack formal …