Investigating the Biological Effect of Multidimensional Ti3C2 (MXene)-Based Nanomaterials through a Metabolomics Approach: a Multidimensional-Determined …

D Zhang, X Li, W Zheng, L Gui, Y Yang, A Li… - Chemistry of …, 2022 - ACS Publications
Multidimensional Ti3C2 (MXene)-based nanomaterials (m-MBNs, including nanosheets and
quantum dots (QDs)) are vitally important transition-metal carbides or carbonitrides with …

Investigating the effect of Ti3C2 (MXene) nanosheet on human umbilical vein endothelial cells via a combined untargeted and targeted metabolomics approach

D Zhang, W Zheng, X Li, A Li, N Ye, L Zhang, Y Liu… - Carbon, 2021 - Elsevier
Ti 3 C 2 is the first member of two-dimensional (2D) transition metal carbide or carbonitride
(MXene) with excellent photothermal effect in disease treatment on an animal model, which …

Integrated metabolomics revealed the photothermal therapy of melanoma by Mo 2 C nanosheets: toward rehabilitated homeostasis in metabolome combined lipidome

D Zhang, M Wang, Y Li, G Liang, W Zheng… - Journal of Materials …, 2024 - pubs.rsc.org
Melanoma, the most aggressive and life-threatening form of skin cancer, lacks innovative
therapeutic approaches and deeper bioinformation. In this study, we developed a …

Investigating biological effects of multidimensional carboxylated carbon-based nanomaterials on human lung A549 cells revealed via non-targeted metabolomics …

D Zhang, L Zhang, W Zheng, F Wu, J Cheng… - …, 2020 - iopscience.iop.org
The biological responses of multidimensional carboxylated carbon-based nanomaterials (c-
CBNs), including carboxylated graphene, carbon nanotube, and fullerene, on human lung …

Nanometabolomics Elucidated Biological Prospective of Mo4/3B2–x Nanosheets: Toward Metabolic Reprogramming of Amino Acid Metabolism

D Zhang, G Liang, L Gui, W Zheng, Y Zeng… - … Applied Materials & …, 2024 - ACS Publications
Mo4/3B2–x nanosheets are newly developed, and 2D transition metal borides (MBene)
were reported in 2021, but there is no report on their further applications and modification; …

Transition metal oxide‐decorated MXenes as drugless nanoarchitectonics for enriched nanocatalytic chemodynamic treatment

HY Xia, BY Li, YT Ye, SB Wang… - Advanced …, 2024 - Wiley Online Library
Despite their unique characteristics, 2D MXenes with sole photothermal conversion ability
are required to explore their superfluous abilities in biomedicine. The small‐molecule …

Role of reactive oxygen species in the toxicity of two-dimensional nanomaterials: A study on layered Ti3C2 MXenes

M Maruthupandy, M Rethinasabapathy, S Jeon… - Nano Today, 2023 - Elsevier
Abstract Two-dimensional (2D) materials, such as MXenes and graphene, are tested as
catalysts, sensors, and nanomedicine, but their safety and biocompatibility are poorly …

Preclinical Toxicity Assessment of Ti‐Based MXene Nanomaterials for Advanced Theranostic Applications

B Singh, R Bahadur, D Rai… - Advanced …, 2024 - Wiley Online Library
MXene, a novel class of 2D materials, has garnered widespread attention from researchers
worldwide due to its remarkable physicochemical properties. Its exceptional physical …

Chemistry of two-dimensional MXene nanosheets in theranostic nanomedicine

Y Wang, W Feng, Y Chen - Chinese Chemical Letters, 2020 - Elsevier
Transition metal carbide, carbonitride and nitride MXenes, as the emerging two-dimensional
(2D) nanomaterials, have aroused burgeoning research interest in a broad range of …

Biofunctionalized two-dimensional Ti3C2 MXenes for ultrasensitive detection of cancer biomarker

S Kumar, Y Lei, NH Alshareef… - Biosensors and …, 2018 - Elsevier
In this work, ultrathin Ti 3 C 2-MXene nanosheets were synthesized by minimally intensive
layer delamination methods, and uniformly functionalized with aminosilane (f-Ti 3 C 2 …