[HTML][HTML] Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma—An aggressive and fatal disease
A Stirnweiss, J Oommen, RS Kotecha, UR Kees… - Oncotarget, 2017 - ncbi.nlm.nih.gov
NUT midline carcinoma (NMC) is a rare and aggressive cancer, with survival typically less
than seven months, that can arise in people of any age. Genetically, NMC is defined by the …
than seven months, that can arise in people of any age. Genetically, NMC is defined by the …
Novel BRD4–NUT fusion isoforms increase the pathogenic complexity in NUT midline carcinoma
K Thompson-Wicking, RW Francis, A Stirnweiss… - Oncogene, 2013 - nature.com
Nuclear protein in testis (NUT)-midline carcinoma (NMC) is a rare, aggressive disease
typically presenting with a single t (15; 19) translocation that results in the generation of a …
typically presenting with a single t (15; 19) translocation that results in the generation of a …
Clinicopathologic features and long-term outcomes of NUT midline carcinoma
DE Bauer, CM Mitchell, KM Strait, CS Lathan… - Clinical cancer …, 2012 - AACR
Purpose: NUT midline carcinoma (NMC) is a poorly differentiated squamous cancer
characterized by rearrangement of the NUT gene. Research advances have provided …
characterized by rearrangement of the NUT gene. Research advances have provided …
Tumor mutation burden and checkpoint immunotherapy markers in NUT midline carcinoma
NUT midline carcinoma (NMC) is a rare, aggressive poorly differentiated carcinoma
genetically defined by NUTM1 gene rearrangement. The purpose of this study was to …
genetically defined by NUTM1 gene rearrangement. The purpose of this study was to …
[HTML][HTML] NUT carcinoma—an underdiagnosed malignancy
UM Lauer, M Hinterleitner, M Horger… - Frontiers in …, 2022 - frontiersin.org
NUT carcinoma (NC) is a rare and highly aggressive malignancy with a dismal prognosis
and a median survival of 6–9 months only. Although very few cases of NC are reported each …
and a median survival of 6–9 months only. Although very few cases of NC are reported each …
NUT midline carcinoma: current concepts and future perspectives of a novel tumour entity
M Salati, C Baldessari, LR Bonetti, C Messina… - Critical Reviews in …, 2019 - Elsevier
NMC is a recently recognized cancer type hallmarked by chromosomal translocation
involving the NUT gene, a catastrophic event leading to fusion oncoprotein responsible for …
involving the NUT gene, a catastrophic event leading to fusion oncoprotein responsible for …
Report of the first international symposium on NUT carcinoma
NUT carcinoma is a rare, aggressive cancer defined by rearrangements of the NUTM1 gene.
No routinely effective treatments of NUT carcinoma exist, despite harboring a targetable …
No routinely effective treatments of NUT carcinoma exist, despite harboring a targetable …
A novel prognostic risk classification model for NUT midline carcinoma: a largest cohort analysis from the NMC registry.
6085 Background: NUT midline carcinoma (NMC) is a rare subtype of squamous cancer
defined by rearrangement of the NUT gene. Due to its rarity and under-diagnosis, there are …
defined by rearrangement of the NUT gene. Due to its rarity and under-diagnosis, there are …
NUT midline carcinoma
CA French - Cancer genetics and cytogenetics, 2010 - Elsevier
NUT midline carcinoma (NMC) is a rare, aggressive human cancer, genetically defined by
rearrangements of the gene NUT (HUGO symbol: C15orf55). In the majority (∼ 75%) of …
rearrangements of the gene NUT (HUGO symbol: C15orf55). In the majority (∼ 75%) of …
Uncommon somatic mutations in metastatic NUT midline carcinoma
S Cavalieri, A Stathis, A Fabbri, A Sonzogni… - Tumori …, 2017 - journals.sagepub.com
Introduction NUT midline carcinoma (NMC) is a rare and aggressive epithelial cancer
arising from median organs. It is driven by chromosomal translocation t (15; 19) involving the …
arising from median organs. It is driven by chromosomal translocation t (15; 19) involving the …