Mitochondria are important cytoplasmic elements present in eukaryotic cells, and are
involved in converting energy to ATP through oxidative phosphorylation. Mitochondria are …

Mitochondria are central organelles in the homeostasis of the cardiovascular system via the
integration of several physiological processes, such as ATP generation via oxidative …

Introduction: One target of toxicity caused by cardiac drugs is the mitochondrion. This review
focuses on the mitochondrion-toxic effects of cardiac drugs and the extent to which …

Despite a high prevalence of sudden cardiac death throughout the world, the mechanisms
that lead to ventricular arrhythmias are not fully understood. Over the last 20 years, a …

High-throughput applicable screens for identifying drug-induced mitochondrial impairment
are necessary in the pharmaceutical industry. Hence, we evaluated the XF96 Extracellular …

Cardiotoxicity represents an adverse side-effect of drugs and a potentially life-threatening
response to toxic compounds and pollutants [1]. Due to the abundance of mitochondria in …

Amiodarone, bi-iodinated benzofuran derivative, is one of the most frequently prescribed
and efficacious antiarrhythmic drugs. Despite its low incidence, amiodarone-induced …

Mitochondria have long been recognized for their central role in energy transduction and
apoptosis. More recently, extensive work in multiple laboratories around the world has …

Introduction When confronted to stress or pathological conditions, the mitochondria
overproduce reactive species that participate in the cellular dysfunction. These organelles …

Propranolol and atenolol are known as β receptor blocker drugs. These drugs are used to
treat some heart diseases. There are controversies in the relationship between the use of …