Amiodarone is an effective class III antiarrhythmic drug, however, the pulmonary toxicity is
one of the most life-threatening complications of its use. The present study was designed to …

Carvedilol ({1–[carbazolyl–(4)-oxy]-3-[2-methoxyphenoxyethyl) amino]-propanol-(2)}) has
been shown to protect cardiac mitochondria from oxidative stress. In this work we examined …

Background Anthracycline-induced cardiotoxicity (AIC) debilitates quality of life in cancer
survivors. Serial characterizations are lacking of the molecular processes occurring with AIC …

Aims It is still unclear why anthracycline treatment results in a cardiac-specific myopathy. We
investigated whether selective doxorubicin (DOX) cardiotoxicity involving mitochondrial …

The process of mitochondrial dynamics is emerging as a core player in cardiovascular
homeostasis. This process refers to the co‐ordinated cycles of biogenesis, fusion, fission …

Anthracycline-based chemotherapy can result in the development of a cumulative and
progressively developing cardiomyopathy. Doxorubicin is one of the most highly prescribed …

Mitochondrial dysfunction is a hallmark of common cardiovascular disorders, including
ischemia–reperfusion injury, hypertrophy, heart failure, and diabetes mellitus. While the role …

Full article: Mitochondria and arrhythmias Skip to Main Content Taylor and Francis Online
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Anthracyclines is an effective chemotherapeutic treatment used for many types of cancer.
However, high cumulative dosage of anthracyclines leads to cardiac toxicity and heart …

Mitochondria are essential to providing ATP, thereby satisfying the energy demand of the
incessant electrical activity and contractile action of cardiac muscle. Emerging evidence …