It has been reported that at the end stage, apoptosis is involved in the progression of heart
failure. It is suggested that cardiac energy metabolism is impaired during the progression of …

The progressive consumption growth of non-steroidal anti-inflammatory drugs (NSAIDs) has
progressively raised the attention toward the gastrointestinal, renal, and cardiovascular …

Acetaminophen and ibuprofen are widely used over-the-counter medications to reduce
fever, pain, and inflammation. Although both drugs are safe in therapeutic concentrations …

Mitochondria have long been recognized as the generators of energy for the cell. Like any
other power source, however, mitochondria are highly vulnerable to inhibition or uncoupling …

The aim of this work was to compare hepatocellular toxicity and pharmacological activity of
amiodarone (2-n-butyl-3-[3, 5 diiodo-4-diethylaminoethoxybenzoyl]-benzofuran; B2-O-Et-N …

Amiodarone is a widely used antiarrhythmic drug that can cause the development of
steatohepatitis as well as liver fibrosis and cirrhosis. The molecular mechanisms of …

The aim of this study was to determine whether amlodipine and/or perindoprilate injected
intravenously (iv) prior to ischemia exerted protective effects on mitochondria structural and …

Mitochondria, responsible for energy metabolism within the cell, act as signaling organelles.
Mitochondrial dysfunction may lead to cell death and oxidative stress and may disturb …

We aimed to detect whether the effect of apigenin (Apig) on the myocardial infarction-
induced cardiomyocyte injury of mouse myocardial cells and acute myocardial infarction …

Metabolic and cardiovascular disease patients have increased plasma levels of lipids and,
specifically, of palmitate, which can be toxic for several tissues. Trimetazidine (TMZ), a …