CEACAM is not necessary for Neisseria gonorrhoeae to adhere to and invade female genital epithelial cells

KV Swanson, GA Jarvis, GF Brooks… - Cellular …, 2001 - Wiley Online Library
Neisseria gonorrhoeae has a repertoire of up to 11 opacity‐associated (Opa) proteins that
are adhesins. Most Opa proteins adhere to CEACAM antigens and when CEACAM …

Specific binding to differentially expressed human carcinoembryonic antigen-related cell adhesion molecules determines the outcome of Neisseria gonorrhoeae …

EA Islam, VC Anipindi, I Francis… - Infection and …, 2018 - Am Soc Microbiol
The gonococcal Opa proteins are an antigenically variable family of surface adhesins that
bind human carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) …

Nuclear Factor-κB Directs Carcinoembryonic Antigen-related Cellular Adhesion Molecule 1 Receptor Expression inNeisseria gonorrhoeae-infected Epithelial Cells

P Muenzner, O Billker, TF Meyer… - Journal of Biological …, 2002 - ASBMB
The human-specific pathogen Neisseria gonorrhoeae expresses opacity-associated (Opa)
protein adhesins that bind to various members of the carcinoembryonic antigen-related …

Engulfment of Neisseria gonorrhoeae: Revealing Distinct Processes of Bacterial Entry by Individual Carcinoembryonic Antigen-Related Cellular Adhesion Molecule …

SE McCaw, EH Liao, SD Gray-Owen - Infection and immunity, 2004 - Am Soc Microbiol
Individual Neisseria gonorrhoeae colony opacity-associated (Opa) protein variants can bind
up to four different carcinoembryonic antigen-related cellular adhesion molecule (CEACAM) …

[PDF][PDF] Specific binding to differentially-expressed human CEACAMs determines the outcome of Neisseria gonorrhoeae infections along the female reproductive tract

EA Islam, VC Anipindi, I Francis… - Infect …, 2018 - researchgate.net
The gonococcal Opa proteins are an antigenically variable family of surface adhesins that
bind 27 human CEACAM1, CEACAM3, CEACAM5 and/or CEACAM6, cell surface …

Innate recognition by neutrophil granulocytes differs between Neisseria gonorrhoeae strains causing local or disseminating infections

A Roth, C Mattheis, P Muenzner, M Unemo… - Infection and …, 2013 - Am Soc Microbiol
Members of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family
serve as cellular receptors for Neisseria gonorrhoeae. More specifically, neisserial colony …

Differential recognition of members of the carcinoembryonic antigen family by Opa variants of Neisseria gonorrhoeae

MP Bos, F Grunert, RJ Belland - Infection and immunity, 1997 - Am Soc Microbiol
Opacity (Opa) protein variation in Neisseria gonorrhoeae is implicated in the pathogenesis
of gonorrhea, possibly by mediating adherence and entry of the bacteria into human tissues …

Uropathogenic E. coli Exploit CEA to Promote Colonization of the Urogenital Tract Mucosa

P Muenzner, A Kengmo Tchoupa, B Klauser… - PLoS …, 2016 - journals.plos.org
Attachment to the host mucosa is a key step in bacterial pathogenesis. On the apical surface
of epithelial cells, members of the human carcinoembryonic antigen (CEA) family are …

CEACAM1 dynamics during Neisseria gonorrhoeae suppression of CD4+ T lymphocyte activation

HSW Lee, MA Ostrowski… - The Journal of …, 2008 - journals.aai.org
Neisseria gonorrhoeae colony opacity-associated (Opa) proteins bind to human
carcinoembryonic antigen cellular adhesion molecules (CEACAM) found on host cells …

Imaging Flow Cytometry Analysis of CEACAM Binding to Opa‐Expressing Neisseria gonorrhoeae

LM Werner, A Palmer, A Smirnov… - Cytometry Part …, 2020 - Wiley Online Library
Human carcinoembryonic antigen‐related cell adhesion molecules (CEACAMs) are a family
of receptors that mediate intercellular interactions. Pathogenic bacteria have ligands that …