The effect of melatonin on sheep endometrial epithelial cell apoptosis through the receptor and non-receptor pathways

H Duan, S Yang, J Zeng, J Lv, L Zhang, X Du… - General and …, 2023 - Elsevier
Melatonin potentially regulates the female animal reproductive function, but its regulatory
mechanism in the apoptosis of sheep endometrial epithelial cells (SEECs) remains to be …

Melatonin protects sheep endometrial epithelial cells against lipopolysaccharide‐induced inflammation in vitro

W Ge, H Duan, J Zeng, X Zhao, J Li… - … in Domestic Animals, 2022 - Wiley Online Library
Melatonin has known anti‐inflammatory effects. Yet, how melatonin protects sheep
endometrial epithelial cells from inflammation remains unknown. In this study, we …

Melatonin suppresses apoptosis and stimulates progesterone production by bovine granulosa cells via its receptors (MT1 and MT2)

SJ Wang, WJ Liu, CJ Wu, FH Ma, S Ahmad, BR Liu… - Theriogenology, 2012 - Elsevier
Melatonin and its receptors have been detected in the ovary of many species, and mediate
ovarian functions. The present study was designed to investigate the expression and …

Role of Melatonin in Ovarian Function. Animals 2024, 14, 644

G Basini, F Grasselli - 2024 - europepmc.org
Melatonin is a hormone mainly produced by the pineal gland in the absence of light stimuli.
The light, in fact, hits the retina, which sends a signal to the suprachiasmatic nucleus, which …

Melatonin modulates the functions of porcine granulosa cells via its membrane receptor MT2 in vitro

YM He, HH Deng, MH Shi, BM Bodinga… - Animal reproduction …, 2016 - Elsevier
Abstract Melatonin (N-acetyl-5-methoxytryptamine) is documented as a hormone involved in
the circadian regulation of physiological and neuroendocrine function in mammals. Herein …

Effect of melatonin on regulation of apoptosis and steroidogenesis in cultured buffalo granulosa cells

H Riaz, MR Yousuf, A Liang, GH Hua… - Animal Science …, 2019 - Wiley Online Library
This study was aimed to address melatonin receptor expression, mRNA level of
hypothalamus and hypophysis hormone receptors (Gn RHR, FSHR, and LHR) …

Melatonin regulates proliferation and apoptosis of endometrial stromal cells via MT1

L Cui, F Xu, Z Jiang, S Wang, X Li… - Acta Biochimica et …, 2021 - academic.oup.com
Endometrial dysfunction is an important factor for implantation failure. The function of the
endometrium is regulated by multiple factors like sex hormones and circadian rhythms …

The inhibitory effect of melatonin on mammary function of lactating dairy goats

W Zhang, J Chen, Y Zhao, Z Zheng… - Biology of …, 2019 - academic.oup.com
The direct role of melatonin in mammary glands of dairy goats has remained obscure. This
study aimed to evaluate the expression of melatonin membrane receptors (MT1 and MT2) in …

Melatonin promotes progesterone secretion in sheep luteal cells by regulating autophagy via the AMPK/mTOR pathway

H Duan, S Yang, L Xiao, S Yang, Z Yan, F Wang, X Ma… - Theriogenology, 2024 - Elsevier
The corpus luteum is primarily responsible for the production and secretion of progesterone.
Melatonin has been established to regulate autophagy and induce progesterone secretion …

Melatonin reduces LH, 17 beta-estradiol and induces differential regulation of sex steroid receptors in reproductive tissues during rat ovulation

LG A Chuffa, FRF Seiva, WJ Fávaro… - Reproductive Biology …, 2011 - Springer
Background Melatonin is associated with direct or indirect actions upon female reproductive
function. However, its effects on sex hormones and steroid receptors during ovulation are …