From pituitary adenoma to pituitary neuroendocrine tumors: how molecular pathways may impact the therapeutic management?

S Chiloiro, L De Marinis - Endocrine, Metabolic & Immune …, 2021 - ingentaconnect.com
The classification of adeno-pituitary tumor was deeply revised over the last 20 years, in
order to better describe the variable and complex biological and clinical behavior of these …

Grading and staging for pituitary neuroendocrine tumors

C Villa, MF Birtolo, PR Louis‐Gustavo, A Righi… - Brain …, 2024 - Wiley Online Library
Pituitary adenoma/pituitary neuroendocrine tumors (PitNETs) are the second most common
primary intracranial tumor and the most frequent neuroendocrine tumors/neoplasms of the …

[HTML][HTML] Role of tumor microenvironment in pituitary neuroendocrine tumors: New approaches in classification, diagnosis and therapy

DA Tapoi, ML Popa, C Tanase, D Derewicz… - Cancers, 2023 - mdpi.com
Simple Summary Pituitary adenomas are highly prevalent intracranial neoplasms that can
be locally invasive in up to half of cases. Consequently, using the term “PitNETs”(pituitary …

Pituitary adenoma or neuroendocrine tumour: the need for an integrated prognostic classification

KKY Ho, UB Kaiser, P Chanson, M Gadelha… - Nature Reviews …, 2023 - nature.com
In the 2022 fifth edition of the WHO Classification of Endocrine Tumours and of Central
Nervous System Tumours, pituitary adenomas are reclassified as neuroendocrine tumours …

A standardised diagnostic approach to pituitary neuroendocrine tumours (PitNETs): a European Pituitary Pathology Group (EPPG) proposal

C Villa, A Vasiljevic, ML Jaffrain-Rea, O Ansorge… - Virchows Archiv, 2019 - Springer
Abstract The 2017 World Health Organization (WHO) classification proposes to type and
subtype primary adenohypophyseal tumours according to their cell lineages with the aim to …

[HTML][HTML] Pituitary neuroendocrine tumors: tumorigenesis, pathogenesis, diagnosis and targeted therapy, from bench to bedside

H Lyu, DL Li, YR Yang, Y Yao, H Wang… - Frontiers in …, 2024 - frontiersin.org
Pituitary neuroendocrine tumors (PitNETs) were previously classified as adenomas and
accordingly referred to as pituitary adenomas. PitNETs have a lifetime prevalence of 5–10 …

[HTML][HTML] Pituitary Neuroendocrine Tumor: Is It Benign or Malignant?

CH Lee, YS Lee - Brain Tumor Research and Treatment, 2023 - synapse.koreamed.org
Abstract The World Health Organization (WHO) updated the classification of pituitary tumors
in 2022. The new classification presents detailed histological subtyping of a pituitary …

Proposal of a clinically relevant working classification of pituitary neuroendocrine tumors based on pituitary transcription factors

S Silva-Ortega, A García-Martinez, MN de Jaime… - Human Pathology, 2021 - Elsevier
The immunohistochemistry (IHC) characterization of pituitary transcription factors (PTFs)
PIT1, TPIT, and SF1, which enable the identification of three different adenohypophyseal cell …

[HTML][HTML] Architects of pituitary tumour growth

ME Sabatino, E Grondona, AL De Paul - Frontiers in endocrinology, 2022 - frontiersin.org
The pituitary is a master gland responsible for the modulation of critical endocrine functions.
Pituitary neuroendocrine tumours (PitNETs) display a considerable prevalence of 1/1106 …

[HTML][HTML] Update on Current Evidence for the Diagnosis and Management of Nonfunctioning Pituitary Neuroendocrine Tumors

E Whyte, M Nezu, C Chik… - Endocrinology and …, 2023 - synapse.koreamed.org
Pituitary neuroendocrine tumors (PitNETs) are the third most frequently diagnosed
intracranial tumors, with nonfunctioning PitNETs (nfPitNETs) accounting for 30% of all …