During infection the SARS-CoV-2 virus fuses its viral envelope with cellular membranes of
its human host. The viral spike (S) protein mediates both the initial contact with the host cell …

Infection of human cells by the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV2) relies on its binding to a specific receptor and subsequent fusion of the viral and host …

Cell entry by SARS-CoV-2 is accomplished by the S2 subunit of the spike S protein on the
virion surface by capture of the host cell membrane and fusion with the viral envelope …

Membrane fusion, a key step in the early stages of virus propagation, allows the release of
the viral genome in the host cell cytoplasm. The process is initiated by fusion peptides that …

The SARS-CoV-2 spike protein is the primary antigenic determinant of the virus and has
been studied extensively, yet the process of membrane fusion remains poorly understood …

SARS‐CoV‐2 may enter target cells through the process of membrane fusion at either the
plasma (~ pH 7.4–7.0) or endosomal (~ pH 6.5–5.0) membrane in order to deliver its genetic …

Cell penetration after recognition of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) virus by the ACE2 receptor and the fusion of its viral envelope membrane …

The receptor binding and proteolysis of Spike of SARS-CoV-2 release its S2 subunit to
rearrange and catalyze viral-cell fusion. This deploys the fusion peptide for insertion into the …

SARS-CoV-2 cell entry is completed after viral spike (S) protein–mediated membrane fusion
between viral and host cell membranes. Stable prefusion and postfusion S structures have …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly contagious, and
transmission involves a series of processes that may be targeted by vaccines and …