Emerging epigenetic targets in rheumatoid arthritis

RR Barik, LK Bhatt - Rheumatology International, 2021 - Springer
Rheumatoid arthritis is a complex disorder that is characterized by irreversible and
progressive destructions of joints, but its exact etiology remains mainly unknown. The …

Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases?

U Oppermann - Arthritis research & therapy, 2013 - Springer
In its widest sense, the term epigenetics describes a range of mechanisms in genome
function that do not solely result from the DNA sequence itself. These mechanisms comprise …

Epigenetics in rheumatoid arthritis: a primer for rheumatologists

N Bottini, GS Firestein - Current rheumatology reports, 2013 - Springer
Epigenetic anomalies are emerging as key pathogenic features of rheumatoid arthritis (RA).
The effect of epigenetics in RA ranges from contributing to complex disease mechanisms to …

Cell-specific epigenetic drivers of pathogenesis in rheumatoid arthritis

N Nair, A Barton, AG Wilson - Epigenomics, 2021 - Future Medicine
Rheumatoid arthritis is a complex, inflammatory autoimmune disease, which is
characterized by pain, swelling and joint damage driven by the altered behavior of a number …

New insights into the epigenetics of inflammatory rheumatic diseases

E Ballestar, T Li - Nature Reviews Rheumatology, 2017 - nature.com
Over the past decade, awareness of the importance of epigenetic alterations in the
pathogenesis of rheumatic diseases has grown in parallel with a general recognition of the …

Epigenetics in the pathogenesis of rheumatoid arthritis

TT Glant, K Mikecz, TA Rauch - BMC medicine, 2014 - Springer
An increasing number of studies show that besides the inherited genetic architecture (that is,
genomic DNA), various environmental factors significantly contribute to the etiology of …

Epigenetic changes in the pathogenesis of rheumatoid arthritis

MV Nemtsova, DV Zaletaev, IV Bure… - Frontiers in …, 2019 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects about 1% of the
world's population. The etiology of RA remains unknown. It is considered to occur in the …

Assessing the potential of epigenetic targets as biomarkers in the diagnosis and treatment of rheumatoid arthritis

N Nair, AG Wilson - Expert Review of Clinical Immunology, 2023 - Taylor & Francis
Introduction Although there are gold-standard diagnostic guidelines and effective treatments
to slow the disease progression of rheumatoid arthritis (RA), approximately 40% of patients …

Rheumatoid arthritis and epigenetics

K Klein, E Karouzakis, S Gay - The Epigenetics of Autoimmunity, 2018 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory disease of the joints, which leads to
cartilage damage, bone erosion, and subsequent joint deformation and loss of function …

Epigenetics of inflammatory arthritis

D Hammaker, GS Firestein - Current opinion in rheumatology, 2018 - journals.lww.com
Epigenetics of inflammatory arthritis : Current Opinion in Rheumatology Epigenetics of
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