Extraesophageal manifestations of gastroesophageal reflux disease

C Hom, MF Vaezi - Gastroenterology Clinics, 2013 - gastro.theclinics.com
Gastroesophageal reflux disease (GERD) is an acid-based disorder that presents with a
wide spectrum of symptoms. In 2006, the modified Delphi process was used to define GERD …

Factors that influence therapeutic outcomes in symptomatic gastroesophageal reflux disease

EMM Quigley - Official journal of the American College of …, 2003 - journals.lww.com
The term “symptomatic gastroesophageal reflux disease”(GERD) refers to those patients
who present with the typical GERD symptoms of heartburn and regurgitation, yet do not have …

[HTML][HTML] Heterogeneity of endoscopy negative heartburn: epidemiology and natural history

F Pace, V Casini, S Pallotta - World Journal of Gastroenterology …, 2008 - ncbi.nlm.nih.gov
It has now become clear that only about 40% or less of patients with heartburn and/or
regurgitation have esophagitis, and that the majority of them lack visible distal esophageal …

White paper AGA: Optimal strategies to define and diagnose gastroesophageal reflux disease

MF Vaezi, JE Pandolfino, MF Vela… - Clinical …, 2017 - cghjournal.org
Gastroesophageal reflux disease (GERD) is a com-mon condition affecting up to 20% of the
Western world. 1 It is a condition that develops when reflux of gastric contents causes …

Management of refractory typical GERD symptoms

E Scarpellini, D Ang, A Pauwels, A De Santis… - Nature Reviews …, 2016 - nature.com
The management of patients with refractory GERD (rGERD) is a major clinical challenge for
gastroenterologists. In up to 30% of patients with typical GERD symptoms (heartburn and/or …

Esophageal-reflux monitoring

JE Pandolfino, MF Vela - Gastrointestinal endoscopy, 2009 - giejournal.org
It is neither practical nor necessary to initiate a diagnostic evaluation of every patient with
symptoms of GERD. Management, by and large, is focused on empiric therapy, with lifestyle …

Endoscopy of the esophagus in gastroesophageal reflux disease: are we losing sight of symptoms? Another perspective

P Sharma, W Chey, R Hunt, L Laine… - Diseases of the …, 2009 - academic.oup.com
Gastroesophageal reflux disease (GERD) is an extremely common chronic disorder
associated with impaired quality of life and huge economic burden. Recently, an …

Patients with refractory reflux symptoms often do not have GERD

TVK Herregods, M Troelstra… - …, 2015 - Wiley Online Library
Background In patients with typical reflux symptoms that persist despite proton pump
inhibitors (PPI s) it is sometimes overlooked that treatment fails due to the presence of other …

[HTML][HTML] Personalized Approach in the Work-up and Management of GERD

R Yadlapati, JE Pandolfino - Gastrointestinal endoscopy clinics of …, 2020 - ncbi.nlm.nih.gov
Gastroesophageal reflux disease (GERD) affects one in five Americans and is one of the
most common diagnoses managed in the outpatient gastroenterology clinic. 1, 2 According …

Diagnosis and management of gastroesophageal reflux disease in the primary care setting: can health-related quality of life play a role?

IM Gralnek - The American journal of gastroenterology, 2001 - Elsevier
Gastroesophageal reflux disease (GERD) is increasingly recognized as a significant health
problem in the community leading to medical evaluation, most often by a primary care …