Frontotemporal dementia spectrum: first genetic screen in a Greek cohort

EM Ramos, C Koros, DR Dokuru, V Van Berlo… - Neurobiology of …, 2019 - Elsevier
Frontotemporal dementia (FTD) is a heterogeneous group of neurodegenerative syndromes
associated with several causative and susceptibility genes. Herein, we aimed to determine …

Integrated multi-omics analysis reveals common and distinct dysregulated pathways for genetic subtypes of Frontotemporal Dementia

K Menden, M Francescatto, T Nyima, C Blauwendraat… - bioRxiv, 2020 - biorxiv.org
Understanding the molecular mechanisms underlying frontotemporal dementia (FTD) is
essential for the development of successful therapies. Here, we present Phase 1 of a multi …

Frontotemporal dementia: Clinical features and diagnosis

SE Lee, BL Miller - Uptodate, 2016 - uptodate.com
Frontotemporal dementias (FTDs) are a group of clinically and neuropathologically
heterogeneous neurodegenerative disorders characterized by prominent changes in social …

Frontotemporal dementia: latest evidence and clinical implications

JJ Young, M Lavakumar, D Tampi… - Therapeutic …, 2018 - journals.sagepub.com
Background: Frontotemporal dementia (FTD) describes a cluster of neurocognitive
syndromes that present with impairment of executive functioning, changes in behavior, and …

[HTML][HTML] Dissecting the many faces of frontotemporal dementia: An imaging perspective

M Pengo, E Premi, B Borroni - International Journal of Molecular Sciences, 2022 - mdpi.com
Frontotemporal dementia (FTD) is a heterogeneous clinical and neuropathological disorder
characterized by behavioral abnormalities, executive dysfunctions and language deficits …

[HTML][HTML] Association between risk polymorphisms for neurodegenerative diseases and cognition in colombian patients with frontotemporal dementia

A López-Cáceres, F Cruz-Sanabria, P Mayorga… - Frontiers in …, 2022 - frontiersin.org
Frontotemporal dementia (FTD) is a heterogeneous neurodegenerative disease of presenile
onset. A better characterization of neurodegenerative disorders has been sought by using …

[HTML][HTML] Protein interaction network analysis reveals genetic enrichment of immune system genes in frontotemporal dementia

C Koçoğlu, R Ferrari, M Roes, G Vandeweyer… - Neurobiology of …, 2022 - Elsevier
To further unravel the complex genetic etiology of frontotemporal dementia (FTD), we
hypothesized that interactors of the protein products of known FTD genes might be involved …

Genetic variation in APOE, GRN, and TP53 are phenotype modifiers in frontotemporal dementia

I Rosas, C Martínez, E Coto, J Clarimón, A Lleó… - Neurobiology of …, 2021 - Elsevier
Frontotemporal dementia (FTD) is a clinical, genetic, and pathologic heterogeneous group
of neurodegenerative diseases. In this study, we investigated the role of APOƐ4, rs5848 in …

Crossing borders between frontotemporal dementia and psychiatric disorders: an updated overview

M Vismara, G Cirnigliaro, E Piccoli… - Journal of …, 2020 - content.iospress.com
Frontotemporal dementia (FTD) includes a group of neurocognitive syndromes, clinically
characterized by altered behaviors, impairment of language proficiency, and altered …

Progress in frontotemporal dementia research

X Wang, Y Shen, W Chen - American Journal of Alzheimer's …, 2013 - journals.sagepub.com
Frontotemporal dementia (FTD) is the second most common type of presenile dementia and
is the most common form of dementia with the onset before 60 years of age. Its typical …