Gonorrhea is a sexually transmitted infection, caused by the bacterial pathogen Neisseria
gonorrhea (Ngo) and affects millions of individuals of all age groups across the globe every …

A search of the gonococcal genome database using the known zinc-binding protein (znuA)
sequences from Escherichia coli and Haemophilus influenzae identified an open reading …

Neisseria gonorrhoeae causes the eponymous sexually transmitted infection gonorrhea, a
global disease that afflicts millions of individuals worldwide per year. To date, no effective …

Trace metals such as iron and zinc are vital nutrients known to play key roles in prokaryotic
processes including gene regulation, catalysis, and protein structure. Metal sequestration by …

Zinc is a bivalent cation essential for bacterial growth and metabolism. The human pathogen
Neisseria meningitidis expresses a homologue of the Zinc uptake regulator Zur, which has …

The Neisseria gonorrhoeae f erric u ptake r egulator (Fur) protein controls expression of iron
homeostasis genes in response to intracellular iron levels. In this study, using transcriptome …

Due to its favorable chemical properties, zinc is used as a structural or catalytic cofactor in a
very large number of proteins. Despite the apparent abundance of this metal in all cell types …

Zinc metabolism is critical to maintain bacterial pathogenesis in their respective hosts.
Research has shown that altering the zinc homeostasis of bacteria via mutation of genes …

Neisseria gonorrhoeae causes the sexually-transmitted infection gonorrhea, a global
disease that is difficult to treat and for which there is no vaccine. This pathogen employs an …

Neisseria gonorrhoeae and Neisseria meningitidis are human-specific pathogens in the
Neisseriaceae family that can cause devastating diseases. Although both species inhabit …