Strain breeding and gene complementation strategies for filamentous fungi
PA Wang, JJ Zhong - Process Biochemistry, 2023 - Elsevier
Filamentous fungi produce a variety of unique bioactive metabolites, which are important to
food, medical and agricultural industries. In order to better utilize filamentous fungi for …
food, medical and agricultural industries. In order to better utilize filamentous fungi for …
The expanding CRISPR toolbox for natural product discovery and engineering in filamentous fungi
Covering: up to May 2022 Fungal genetics has transformed natural product research by
enabling the elucidation of cryptic metabolites and biosynthetic steps. The enhanced …
enabling the elucidation of cryptic metabolites and biosynthetic steps. The enhanced …
CRISPR/Cas9‐based genome engineering: A new breakthrough in the genetic manipulation of filamentous fungi
Filamentous fungi have several industrial, environmental, and medical applications.
However, they are rarely utilized owing to the limited availability of full‐genome sequences …
However, they are rarely utilized owing to the limited availability of full‐genome sequences …
Strategies for gene disruption and expression in filamentous fungi
YZ Mei, YL Zhu, PW Huang, Q Yang, CC Dai - Applied microbiology and …, 2019 - Springer
Filamentous fungi can produce many valuable secondary metabolites; among these fungi,
endophytic fungi play an ecological role in mutualistic symbiosis with plants, including …
endophytic fungi play an ecological role in mutualistic symbiosis with plants, including …
CRISPR-Cas9 system for functional genomics of filamentous fungi: applications and challenges
Functional genomics enhances the understanding of fundamental fungal biology and aids in
improving the production of valuable bioactive fungal compounds. Available gene …
improving the production of valuable bioactive fungal compounds. Available gene …
[HTML][HTML] Genetic Engineering of Filamentous Fungi: Prospects for Obtaining Fourth-Generation Biological Products
LR Oliveira, AR Gonçalves, ED Quintela… - Applied …, 2024 - mdpi.com
Filamentous fungi exhibit unparalleled potential as cell factories for protein production,
owing to their adeptness in protein secretion and remarkable proficiency in post …
owing to their adeptness in protein secretion and remarkable proficiency in post …
Progress of the CRISPR/Cas system and the next-generation CRISPR technologies in gene editing for filamentous fungi
C Yingying, LIU Yang, SHI Junjie… - Synthetic Biology …, 2024 - synbioj.cip.com.cn
Filamentous fungi, which harbor distinct morphology and cell structure, play a critical role in
human health and industrial/agricultural production. However, the unique characteristics of …
human health and industrial/agricultural production. However, the unique characteristics of …
[HTML][HTML] The CRISPR/Cas9 system for targeted genome engineering in free-living fungi: advances and opportunities for lichenized fungi
K Shanmugam, S Ramalingam… - Frontiers in …, 2019 - frontiersin.org
Studies using whole genome sequencing, computational and gene expression, targeted
genome engineering techniques for generating site-specific sequence alterations through …
genome engineering techniques for generating site-specific sequence alterations through …
[HTML][HTML] CRISPR/Cas9 genome editing technology in filamentous fungi: progress and perspective
R Song, Q Zhai, L Sun, E Huang, Y Zhang… - Applied microbiology …, 2019 - Springer
Filamentous fungi play an important role in human health and industrial/agricultural
production. With the increasing number of full genomes available for fungal species, the …
production. With the increasing number of full genomes available for fungal species, the …
[HTML][HTML] Applications of CRISPR/Cas9 in the synthesis of secondary metabolites in filamentous fungi
C Jiang, G Lv, Y Tu, X Cheng, Y Duan… - Frontiers in …, 2021 - frontiersin.org
Filamentous fungi possess the capacity to produce a wide array of secondary metabolites
with diverse biological activities and structures, such as lovastatin and swainsonine. With the …
with diverse biological activities and structures, such as lovastatin and swainsonine. With the …