We designed a unique nanocapsule for efficient single CRISPR-Cas9 capsuling,
noninvasive brain delivery and tumor cell targeting, demonstrating an effective and safe …

CRISPR/Cas9 gene-editing technology shows great potential for treating a variety of
diseases, such as glioblastoma multiforme (GBM). However, CRISPR components suffer …

Radiotherapy is a mainstay of glioblastoma (GBM) treatment; however, the development of
therapeutic resistance has hampered the efficacy of radiotherapy, suggesting that additional …

Harnessing CRISPR-Cas9 technology for cancer therapeutics has been hampered by low
editing efficiency in tumors and potential toxicity of existing delivery systems. Here, we …

CRISPR/Cas9 genome editing has gained rapidly increasing attentions in recent years,
however, the translation of this biotechnology into therapy has been hindered by efficient …

Delivery technologies for the CRISPR-Cas9 (CRISPR, clustered regularly interspaced short
palindromic repeats) gene editing system often require viral vectors, which pose safety …

Clustered regularly interspaced short palindromic repeats/associated protein 9
(CRISPR/Cas9) gene‐editing technology shows promise for manipulating single or multiple …

The emerging clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-
associated system (Cas) gene-editing system represents a promising tool for genome …

The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein
9 (CRISPR/Cas9) systems have emerged as a robust and versatile genome editing platform …

Genome editing technologies, such as clustered regularly interspaced short palindromic
repeats (CRISPR)/CRISPR-associated (Cas) systems, are being widely applied in …