Molecular mechanisms in the etiology of polycystic ovary syndrome (PCOS): A multifaceted hypothesis towards the disease with potential therapeutics

KU Nisa, N Tarfeen, SA Mir, AA Waza… - Indian Journal of Clinical …, 2024 - Springer
Among the premenopausal women, Polycystic Ovary Syndrome (PCOS) is the most
prevalent endocrinopathy affecting the reproductive system and metabolic rhythms leading …

[PDF][PDF] Pathomechanisms of polycystic ovary syndrome: multidimensional approaches

P Sagvekar, R Dadachanji, K Patil… - Front Biosci (Elite …, 2018 - researchgate.net
Polycystic ovary syndrome is a complex endocrine disorder affecting numerous women of
reproductive age across the globe. Characterized mainly by irregular menses, hirsutism …

[HTML][HTML] In search of new therapeutics—molecular aspects of the PCOS pathophysiology: genetics, hormones, metabolism and beyond

A Wawrzkiewicz-Jałowiecka, K Kowalczyk… - International Journal of …, 2020 - mdpi.com
In a healthy female reproductive system, a subtle hormonal and metabolic dance leads to
repetitive cyclic changes in the ovaries and uterus, which make an effective ovulation and …

Polycystic ovarian syndrome: pathophysiology, molecular aspects and clinical implications

E Diamanti-Kandarakis - Expert Reviews in molecular medicine, 2008 - cambridge.org
Polycystic ovarian syndrome (PCOS) is universally recognised as the commonest
endocrinopathy of women. The definition and the aetiological hypotheses of PCOS are …

Genetic basis of polycystic ovary syndrome (PCOS): current perspectives

MJ Khan, A Ullah, S Basit - The application of clinical genetics, 2019 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a common infertility disorder affecting a significant
proportion of the global population. It is the main cause of anovulatory infertility in women …

Current and emerging drug treatment strategies for polycystic ovary syndrome

N Helvaci, BO Yildiz - Expert Opinion on Pharmacotherapy, 2023 - Taylor & Francis
Introduction Polycystic ovary syndrome (PCOS) is a common hormonal, metabolic, and
reproductive disorder with a heterogeneous phenotype. As the exact etiology of PCOS is still …

[HTML][HTML] Key signalling pathways underlying the aetiology of polycystic ovary syndrome

KA Walters, A Moreno-Asso, NK Stepto… - Journal of …, 2022 - joe.bioscientifica.com
Polycystic ovary syndrome (PCOS) is a common endocrine condition characterised by a
range of reproductive, endocrine, metabolic and psychological abnormalities. Reports …

Molecular genetics of polycystic ovary syndrome: an update

L Li, KH Baek - Current Molecular Medicine, 2015 - ingentaconnect.com
Polycystic ovary syndrome (PCOS) is a complex genetic disorder caused by interplay
between several 'susceptibility'genes and environment factors. In the past few years …

[HTML][HTML] Polycystic ovarian syndrome: a complex disease with a genetics approach

H Nautiyal, SS Imam, S Alshehri, MM Ghoneim, M Afzal… - Biomedicines, 2022 - mdpi.com
Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder affecting females in
their reproductive age. The early diagnosis of PCOS is complicated and complex due to …

Polycystic ovary syndrome and molecular approaches.

A Aydos, Y Öztemur, B Gür-Dedeoğlu - 2016 - cabidigitallibrary.org
Polycystic ovary syndrome (PCOS) is an endocrine disorder, which affects women at
reproductive age. Syndrome is characterized by hyperandrogenism, polycystic ovarian …