Introduction The extracellular matrix (ECM) plays an integral role in wound healing. It
provides both structure and growth factors that allow for the organised cell proliferation …

Wound closure after post‐traumatic injuries and/or localized at peculiar body sites (head‐
and‐neck, oral cavity, legs) are particularly challenging and can often be delayed due to …

Background: Wound healing is a dynamic process whereby cells, growth factors (GFs), and
the extracellular matrix (ECM) interact to restore the architecture of damaged tissue. Chronic …

Although the principles of burn management are still primarily focused on survival, as
advances are realized in resuscitation, nutrition, and wound management, the functional …

A chronic wound fails to complete an orderly and timely reparative process and places
patients at increased risk for wound complications that negatively impact quality of life and …

Background: Use of biologically engineered acellular dermal matrices in the upper and
lower extremities is increasingly recognized as a means of achieving definitive healing in …

The pronounced effect of extracellular matrix (ECM) scaffolds in supporting tissue
regeneration is related mainly to their maintained 3D structure and their bioactive …

Acellular dermal matrix (ADM) is a recently-developed, biologically-derived product with
many useful applications in plastic surgery, in both cosmetic and reconstructive procedures …

Summary Background Dermal regenerative matrices (DRMs) have been used for several
decades in the treatment of acute and reconstructive burn injury. The objective of this study …

Modern advances in tissue engineering have transformed the plastic surgeon's
management strategies across a wide variety of applications. Comprehension of the …