Abstract Learning Objectives After completing this course, the reader will be able to:
Describe the evolution of cancer chemotherapy for patients with colorectal cancer. Discuss …

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Abstract Learning Objectives After completing this course, the reader should be able to: Use
the evolving treatment strategies in metastatic colorectal cancer, including key data from …

The treatment of metastatic colorectal cancer (mCRC) has evolved significantly over the past
10 years. For nearly 40 years, the fluoropyrimidine 5-fluorouracil (5-FU) was the only agent …

Important developments in chemotherapy for metastatic colorectal cancer over the last years
are reviewed, with an emphasis on the most recently published data from clinical trials. The …

Over the past 8 to 10 years, significant advances have been made in the treatment of
metastatic colorectal cancer (mCRC). In particular, the development of the targeted biologic …

While surgery is the cornerstone treatment for early-stage colorectal cancer, chemotherapy
is the first treatment option for metastatic disease when tumor lesions are frequently not fully …

The survival rate of patients with metastatic colorectal cancer (mCRC) has significantly
improved with applications of molecularly targeted drugs, such as bevacizumab, and led to a …

Treatment algorithms and survival for patients with metastatic colorectal cancer have
changed dramatically over the past decade, largely due to the advent of molecularly …

The management of patients with metastatic colorectal cancer (CRC) has changed
dramatically over the last five years, with increasing chances of prolonged survival. The …