Simple Summary The tumor immune escape mechanisms are key factors in cancer
progression and metastasis. They are an undeniable hurdle for successful cancer treatment …

Recent exciting progress in cancer immunotherapy has ushered in a new era of cancer
treatment. Immunotherapy can elicit unprecedented durable responses in advanced cancer …

Throughout the last decades, dendritic cell (DC)-based anti-tumor vaccines have proven to
be a safe therapeutic approach, although with inconsistent clinical results. The functional …

The cross talk between immune and non-immune cells in the tumor microenvironment leads
to immunosuppression, which promotes tumor growth and survival. Immunotherapy is an …

Tumor immune microenvironment (TIME) include tumor cells, immune cells, cytokines, etc.
The interactions between these components, which are divided into anti-tumor and pro …

Over the past decade, immune checkpoint inhibitor (ICI) therapy has been established as
the standard of care for many types of cancer, but the strategies employed have continued to …

Cancer immunotherapy is demonstrating impressive clinical benefit in different malignancies
and clinical oncologists are increasingly turning their attention to immune-oncology. It is now …

The innate immune sensing pathways play critical roles in the defense against pathogen
infection, but their roles in cancer immunosurveillance and cancer therapies are less …

Dendritic cells (DCs) are professional antigen-presenting cells, orchestrating innate and
adaptive immunity during infections, autoimmune diseases, and malignancies. Since the …

Tumor cells constantly interact with their microenvironment, which comprises a variety of
immune cells together with endothelial cells and fibroblasts. The composition of the tumor …