[HTML][HTML] A hitchhiker's guide to single-cell transcriptomics and data analysis pipelines
Single-cell transcriptomics (SCT) is a tour de force in the era of big omics data that has led to
the accumulation of massive cellular transcription data at an astounding resolution of single …
the accumulation of massive cellular transcription data at an astounding resolution of single …
Quantitative single-cell transcriptomics
C Ziegenhain, B Vieth, S Parekh… - Briefings in …, 2018 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) is currently transforming our understanding of
biology, as it is a powerful tool to resolve cellular heterogeneity and molecular networks …
biology, as it is a powerful tool to resolve cellular heterogeneity and molecular networks …
Single-cell transcriptomics bioinformatics and computational challenges
The emerging single-cell RNA-Seq (scRNA-Seq) technology holds the promise to
revolutionize our understanding of diseases and associated biological processes at an …
revolutionize our understanding of diseases and associated biological processes at an …
Single‐cell sequencing methodologies: from transcriptome to multi‐dimensional measurement
Y Chen, J Song, Q Ruan, X Zeng, L Wu, L Cai… - Small …, 2021 - Wiley Online Library
Cells are the basic building blocks of biological systems, with inherent unique molecular
features and development trajectories. The study of single cells facilitates in‐depth …
features and development trajectories. The study of single cells facilitates in‐depth …
Single-cell RNA sequencing analysis: a step-by-step overview
Thanks to innovative sample-preparation and sequencing technologies, gene expression in
individual cells can now be measured for thousands of cells in a single experiment. Since its …
individual cells can now be measured for thousands of cells in a single experiment. Since its …
Experimental considerations for single-cell RNA sequencing approaches
QH Nguyen, N Pervolarakis, K Nee… - Frontiers in cell and …, 2018 - frontiersin.org
Single-cell transcriptomic technologies have emerged as powerful tools to explore cellular
heterogeneity at the resolution of individual cells. Previous scientific knowledge in cell …
heterogeneity at the resolution of individual cells. Previous scientific knowledge in cell …
From multitude to singularity: An up-to-date overview of scRNA-seq data generation and analysis
Single cell RNA sequencing (scRNA-seq) is today a common and powerful technology in
biomedical research settings, allowing to profile the whole transcriptome of a very large …
biomedical research settings, allowing to profile the whole transcriptome of a very large …
A review of single-cell RNA-Seq annotation, integration, and cell–cell communication
Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool for investigating
cellular biology at an unprecedented resolution, enabling the characterization of cellular …
cellular biology at an unprecedented resolution, enabling the characterization of cellular …
Identifying cell types to interpret scRNA-seq data: how, why and more possibilities
Single-cell RNA sequencing (scRNA-seq) has generated numerous data and renewed our
understanding of biological phenomena at the cellular scale. Identification of cell types has …
understanding of biological phenomena at the cellular scale. Identification of cell types has …
scRNASeqDB: a database for RNA-Seq based gene expression profiles in human single cells
Single-cell RNA sequencing (scRNA-Seq) is rapidly becoming a powerful tool for high-
throughput transcriptomic analysis of cell states and dynamics at the single cell level. Both …
throughput transcriptomic analysis of cell states and dynamics at the single cell level. Both …