Beckwith–Wiedemann syndrome is an overgrowth disorder with an increased risk of
childhood tumors that results from a dysregulation of imprinted gene expression in the …

Background: Beckwith–Wiedemann syndrome (BWS) is a phenotypically and genetically
heterogeneous disorder associated with epigenetic/genetic aberrations on chromosome …

1.6 Analytical methods (MS: methylation-specific) MS-MLPA; MS-Southern-blot; MS-PCR;
MS-single nucleotide primer extension (SNuPE); allele-specific methylation multiplex …

Beckwith–Wiedemann syndrome (BWS) is a clinically heterogeneous overgrowth syndrome
associated with an increased risk for embryonal tumor development. BWS provides an ideal …

Epigenetics has achieved a profound impact in the biomedical field, providing new
experimental opportunities and innovative therapeutic strategies to face a plethora of …

Abstract Purpose Beckwith–Wiedemann syndrome (BWS) is a developmental disorder
caused by dysregulation of the imprinted gene cluster of chromosome 11p15. 5 and often …

Beckwith–Wiedemann syndrome (BWS) is the most common epigenetic overgrowth disorder
and presents with patients affected by a variety of clinical features. Although genotype …

“Parental imprinting” refers to an epigenetic marking of genes that results in monoallelic
expression. This phenomenon plays a critical role in embryogenesis and development. The …

Abstract Background Beckwith-Wiedemann syndrome (BWS) is a congenital overgrowth
disorder associated with abnormalities in 11p15. 5 imprinted genes. The most common …

Abstract Beckwith-Wiedemann Syndrome (BWS; OMIM 130650) is an overgrowth disorder
characterized by macrosomia, macroglossia, organomegaly and developmental …