Potent intracellular antibacterial activity of a marine peptide-N6NH2 and its D-enantiomer against multidrug-resistant Aeromonas veronii

T Li, Z Wang, H Han, D Teng, R Mao, Y Hao… - Applied Microbiology …, 2021 - Springer
Aeromonas veronii can cause a variety of diseases such as sepsis in humans and animals.
However, there has been no effective way to eradicate A. veronii. In this study, the …

Dual Antibacterial Activities and Biofilm Eradication of a Marine Peptide-N6NH2 and Its Analogs against Multidrug-Resistant Aeromonas veronii

T Li, Z Wang, H Han, D Teng, R Mao, Y Hao… - International Journal of …, 2020 - mdpi.com
Aeromonas veronii is one of the main pathogens causing various diseases in humans and
animals. It is currently difficult to eradicate drug-resistant A. veronii due to the biofilm …

Marine Peptide-N6NH2 and Its Derivative-GUON6NH2 Have Potent Antimicrobial Activity Against Intracellular Edwardsiella tarda in vitro and in vivo

H Han, D Teng, R Mao, Y Hao, N Yang… - Frontiers in …, 2021 - frontiersin.org
Edwardsiella tarda is a facultative intracellular pathogen in humans and animals. There is
no effective way except vaccine candidates to eradicate intracellular E. tarda. In this study …

Novel D-form of hybrid peptide (D-AP19) rapidly kills Acinetobacter baumannii while tolerating proteolytic enzymes

P Jariyarattanarach, N Klubthawee, M Wongchai… - Scientific Reports, 2022 - nature.com
Antimicrobial peptides (AMPs) are being developed as potent alternative treatments to
conventional antibiotics which are unlikely to induce bacterial resistance. They can be …

Truncated analog Brevinin2-CE-N26V5K: revelation the augmentation of antimicrobial activity

Y Zhao, X Wang, Y Sun, Z Li, T Liu, Q Liu… - World Journal of …, 2022 - Springer
Abstract Brevinin2-CE (B2CE), a natural peptide containing 37 amino acids, was first
isolated from the skin secretions of the Chinese forest frog Rana chensinensis. B2CE shows …

Improved Antibacterial Activity of the Marine Peptide N6 against Intracellular Salmonella Typhimurium by Conjugating with the Cell-Penetrating Peptide Tat11 via a …

Z Li, D Teng, R Mao, X Wang, Y Hao… - Journal of Medicinal …, 2018 - ACS Publications
The poor penetration ability of antimicrobial agents limits their use in the treatment of
intracellular bacteria. In this study, the conjugate CNC (6) was generated by connecting the …

Antibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis

N Yang, X Liu, D Teng, Z Li, X Wang, R Mao… - Scientific Reports, 2017 - nature.com
Abstract NZ17074 (N1), an arenicin-3 derivative isolated from the lugworm, has potent
antibacterial activity and is cytotoxic. To reduce its cytotoxicity, seven N1 analogues with …

Effective antimicrobial activity of Cbf‐K16 and Cbf‐A7A13 against NDM‐1‐carrying Escherichia coli by DNA binding after penetrating the cytoplasmic membrane in …

Q Hao, H Wang, J Wang, J Dou… - Journal of Peptide …, 2013 - Wiley Online Library
New Delhi metallo‐beta‐lactamase‐1 (NDM‐1)‐carrying isolates, which are resistant to
most clinical used antibiotics except for tigecycline and colistin, have been found worldwide …

Improved Stability and Activity of a Marine Peptide-N6NH2 against Edwardsiella tarda and Its Preliminary Application in Fish

H Han, T Li, Z Wang, D Teng, R Mao, Y Hao, N Yang… - Marine drugs, 2020 - mdpi.com
Edwardsiella tarda can cause fatal gastro-/extraintestinal diseases in fish and humans.
Overuse of antibiotics has led to antibiotic resistance and contamination in the environment …

Production of an Antimicrobial Peptide AN5‐1 in Escherichia coli and its Dual Mechanisms Against Bacteria

T Yi, Y Huang, Y Chen - Chemical biology & drug design, 2015 - Wiley Online Library
AN 5‐1 (YSKSLPLSVLNP) is an antimicrobial peptide isolated from the fermentation broth of
Paenibacillus alvei strain AN 5 (J Ind Microb Biotechnol 2013; 40: 571–9). In this study, we …