Mammalian spermatogenesis is characterized by disproportionate germ cell apoptosis. The
high frequency of apoptosis is considered a safety mechanism that serves to avoid …

Programmed cell death is an evolutionarily conserved cell death process that plays a major
role during normal development and homeostasis. In many cases, the ordered execution of …

Apoptosis is a key event controlling sperm output both in normal and pathological
conditions. However, the mechanisms involving germ cell apoptosis is far from being …

Apoptosis occurs at any time in the ontogeny of the testis, especially during the first wave of
spermatogenesis. However, the exact mechanisms by which homeostasis of apoptosis and …

Mammalian spermatogenesis is a successive process consisting of spermatogonial
proliferation, spermatocytic meiosis, and spermiogenesis, representing the maturation of …

Male germ-cell apoptosis occurs naturally and can be increased by exposure to drugs and
toxic chemicals. Individuals may have different rates of apoptosis and are likely to also …

Spermatogenesis is a dynamic developmental process that includes stem cell proliferation
and differentiation, meiotic cell divisions and extreme chromatin condensation. Although …

The significance of cell death occurring during spermatogenesis is a subject of interest
because of its potential medical importance. Unfortunately, the field has been difficult for …

The problem of male infertility is a global health crisis and poses a serious threat to the well-
being of families. Under heat stress (HS), the reduction of Sertoli cells (SCs) inhibits energy …

Apoptosis is widely known to play a major role on diseases related to male infertility.
Diseases of the male genital tract as defective spermatogenesis, decreased sperm motility …