Iron deficiency in chronic kidney disease: updates on pathophysiology, diagnosis, and treatment

EK Batchelor, P Kapitsinou, PE Pergola… - Journal of the …, 2020 - journals.lww.com
Anemia is a complication that affects a majority of individuals with advanced CKD. Although
relative deficiency of erythropoietin production is the major driver of anemia in CKD, iron …

Disorders of iron metabolism and anemia in chronic kidney disease

B Panwar, OM Gutiérrez - Seminars in nephrology, 2016 - Elsevier
Dysregulated iron homeostasis plays a central role in the development of anemia of chronic
kidney disease (CKD) and is a major contributor toward resistance to treatment with …

Clinical aspects of iron use in the anemia of kidney disease

WH Hörl - Journal of the American Society of Nephrology, 2007 - journals.lww.com
Iron deficiency occurs in the vast majority of patients with chronic kidney disease (CKD). The
causes of iron deficiency in these patients are multifactorial. Main factors that contribute to …

Iron indices in chronic kidney disease in the National Health and Nutritional Examination Survey 1988–2004

S Fishbane, S Pollack, HI Feldman… - Clinical Journal of the …, 2009 - journals.lww.com
Background and objectives: Anemia is a common and early complication of nondialysis
chronic kidney disease (CKD). One contributing factor is iron deficiency, which may be …

Positive iron balance in chronic kidney disease: how much is too much and how to tell?

JB Wish, GR Aronoff, BR Bacon, C Brugnara… - American journal of …, 2018 - karger.com
Background: Regulation of body iron occurs at cellular, tissue, and systemic levels. In
healthy individuals, iron absorption and losses are minimal, creating a virtually closed …

Iron deficiency anemia in chronic kidney disease

A Gafter-Gvili, A Schechter, B Rozen-Zvi - Acta haematologica, 2019 - karger.com
Iron deficiency anemia is a common complication of chronic kidney disease (CKD). CKD
patients suffer from both absolute and functional iron deficiency. Absolute iron deficiency is …

Update on anemia in ESRD and earlier stages of CKD: core curriculum 2018

S Fishbane, B Spinowitz - American Journal of Kidney Diseases, 2018 - Elsevier
Anemia is a frequent complication during the later stages of chronic kidney disease. When
present, it may cause symptoms such as fatigue and shortness of breath. The pathogenesis …

Anemia in renal disease: diagnosis and management

CE Lankhorst, JB Wish - Blood reviews, 2010 - Elsevier
Chronic kidney disease (CKD) is a widespread health problem in the world and anemia is a
common complication. Anemia conveys significant risk for cardiovascular disease, faster …

Overview of iron metabolism in health and disease

S Dev, JL Babitt - Hemodialysis International, 2017 - Wiley Online Library
Iron is an essential element for numerous fundamental biologic processes, but excess iron is
toxic. Abnormalities in systemic iron balance are common in patients with chronic kidney …

Iron supplementation to treat anemia in patients with chronic kidney disease

A Besarab, DW Coyne - Nature Reviews Nephrology, 2010 - nature.com
Iron deficiency is prevalent in patients with chronic kidney disease (CKD), and use of oral
and intravenous iron in patients with CKD who do not require dialysis might obviate or delay …