First‐line cetuximab+ platinum‐based therapy for recurrent/metastatic head and neck squamous cell carcinoma: A real‐world observational study—ENCORE

C Le Tourneau, M Ghiani, MC Cau, R Depenni… - Cancer …, 2023 - Wiley Online Library
Background ENCORE, an observational, prospective, open‐label study, investigated real‐
world treatment practices and outcomes with cetuximab plus platinum‐based therapy (PBT) …

Observational, prospective, phase 4 study in patients with first‐line recurrent and/or metastatic squamous cell carcinoma of the head and neck treated with cetuximab …

J Guigay, E Chamorey, G Lefebvre, M Rotarski… - Cancer …, 2022 - Wiley Online Library
Background Cetuximab plus platinum‐based therapy (PBT) followed by cetuximab
maintenance until progression (EXTREME) is a guideline‐recommended first‐line treatment …

Cetuximab+ platinum-based therapy (PBT) as a first-line treatment for patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M …

C Le Tourneau, M Ghiani, MC Cau… - Annals of …, 2018 - annalsofoncology.org
Background: The EXTREME regimen (cetuximab+ PBT≤ 6 cycles followed by cetuximab-
alone maintenance until progressive disease [PD]) was the first treatment in 30 years to …

The observational ENCORE study: cetuximab+ platinum-based therapy (PBT) for first-line (1L) treatment of patients with recurrent/metastatic squamous cell carcinoma …

C Le Tourneau, M Ghiani, MC Cau… - Annals of …, 2017 - annalsofoncology.org
Background: The randomized, phase 3 EXTREME study established cetuximab+ platinum+
5-flurouracil (5-FU) followed by cetuximab maintenance until progressive disease (PD) as …

[HTML][HTML] Cetuximab, docetaxel, and cisplatin as first-line treatment in patients with recurrent or metastatic head and neck squamous cell carcinoma: a multicenter …

J Guigay, J Fayette, AF Dillies, C Sire, JN Kerger… - Annals of …, 2015 - Elsevier
Background Cetuximab in combination with platinum and 5-fluorouracil is the standard of
care in the first-line treatment of patients with recurrent/metastatic head and neck squamous …

First-line cetuximab plus cisplatin and fluorouracil vs cisplatin and fluorouracil in Chinese patients with recurrent and/or metastatic squamous cell carcinoma of the …

Y Guo, Y Luo, Q Zhang, X Huang, Z Li… - Annals of …, 2018 - annalsofoncology.org
Background: The EXTREME regimen (cetuximab+ platinum+ 5-FU up to 6 cycles followed
by cetuximab maintenance until progression) is the global gold standard of care for 1L R/M …

Cetuximab, docetaxel, and cisplatin (TPEx) as first-line treatment in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN …

J Guigay, J Fayette, A Dillies, C Sire… - Journal of Clinical …, 2011 - ascopubs.org
5567 Background: Cetuximab in combination with platinum and 5FU has become a
standard in first-line treatment of patients (pts) with R/M SCCHN. Cetuximab and taxane …

Platinum‐based chemotherapy plus cetuximab first‐line for Asian patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck: Results of …

Y Guo, M Shi, A Yang, J Feng, X Zhu, YJ Choi… - Head & …, 2015 - Wiley Online Library
Background The purpose of this study was to assess the efficacy, safety, and
pharmacokinetics of cisplatin‐based chemotherapy plus cetuximab as first‐line treatment in …

Cetuximab, docetaxel, and cisplatin (TPEx) as first-line treatment in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN …

J Guigay, J Fayette, AF Dillies, C Sire, JN Kerger… - 2012 - ascopubs.org
5505 Background: Cetuximab in combination with platinum and 5FU (PFEx) has become a
standard in first-line treatment of patients (pts) with R/M SCCHN. Cetuximab and taxane …

Drug Insight: cetuximab in the treatment of recurrent and metastatic squamous cell carcinoma of the head and neck

J Bernier - Nature Clinical Practice Oncology, 2008 - nature.com
Patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck
(SCCHN) have a poor prognosis, particularly those whose disease has progressed on …