Excessive inflammation and impaired healing of cardiac tissue following a myocardial
infarction (MI) can drive the development of heart failure. Cardiac repair begins immediately …

Extensive necrosis of ischemic cardiomyocytes in the infarcted myocardium activates the
innate immune response triggering an intense inflammatory reaction. Release of danger …

Purpose Despite modern reperfusion and pharmacologic therapies, myocardial infarction
(MI) remains a leading cause of morbidity and mortality worldwide. Therefore, the …

Improvements in early interventions after acute myocardial infarction (AMI), notably, the
increased use of timely reperfusion therapy, have increased survival dramatically in recent …

Acute myocardial infarction (MI) causes sterile inflammation, which is characterized by
recruitment and activation of innate and adaptive immune system cells. Here we delineate …

Introduction The immune system plays a crucial role in the initiation, development, and
resolution of inflammation following myocardial infarction (MI). The lack of oxygen and …

Myocardial infarction is the most common cause of cardiac injury and results in acute loss of
a large number of myocardial cells. Because the heart has negligible regenerative capacity …

Growing evidence indicates that overactivation and prolongation of the inflammatory
response after acute myocardial infarction (AMI) result in worse left ventricular remodelling …

Myocardial infarction (MI) is an irreversible damage of the heart muscle, which often leads to
adverse cardiac remodeling and progressive heart failure. After MI, immune cells play a vital …

One of the major therapeutic challenges in the arena of interventional cardiology is to design
strategies aimed at reducing myocardial tissue damage after myocardial infarction. In …