[HTML][HTML] Consolidative durvalumab outcomes in stage III non-small cell lung cancer in a multi-centre study

A Kartolo, H Shah, W Hopman, AS Fung… - Cancer Treatment and …, 2021 - Elsevier
Aim To investigate the impact of PD-L1 expression status on consolidative durvalumab
efficacy and safety in stage III NSCLC patients. Methods This retrospective, ethics board …

[PDF][PDF] Durvalumab in stage III non-small-cell lung cancer

MD Copur, D Gauchan, R Ramaekers - N Engl J Med, 2018 - researchgate.net
To the Editor: Antonia et al.(Nov. 16 issue) 1 found that, among patients with locally
advanced, unresectable, stage III non–small-cell lung cancer (NSCLC), the median …

Patient-reported outcomes with durvalumab after chemoradiotherapy in stage III, unresectable non-small-cell lung cancer (PACIFIC): a randomised, controlled, phase …

R Hui, M Özgüroğlu, A Villegas, D Daniel… - The Lancet …, 2019 - thelancet.com
Background In the ongoing, phase 3 PACIFIC trial, durvalumab improved the primary
endpoints of progression-free survival and overall survival compared with that for placebo …

Effectiveness of durvalumab consolidation in stage III non-small-cell lung cancer: focus on treatment selection and prognostic factors

M Guberina, N Guberina, C Pöttgen, T Gauler… - …, 2022 - Taylor & Francis
The pivotal PACIFIC trial defined durvalumab consolidation as the new standard of care in
patients with stage III non-small-cell lung cancer treated with definitive radiochemotherapy …

[HTML][HTML] Durvalumab in combination with chemoradiotherapy for patients with unresectable stage III non-small-cell lung cancer: Results from the phase 1 CLOVER …

DW Kim, BC Cho, K Pachipala, SW Kim, CL Wang… - Lung Cancer, 2024 - Elsevier
Introduction For patients with unresectable, stage III non-small-cell lung cancer (NSCLC),
current standard of care is concurrent chemoradiotherapy (cCRT) followed by consolidation …

Use of durvalumab in stage III n on‐small‐cell lung cancer based on eligibility for the PACIFIC study

E Boys, B Gao, R Hui, I da Silva, E Hau, H Gee… - Thoracic …, 2023 - Wiley Online Library
Background Durvalumab following concurrent chemoradiotherapy is standard treatment for
unresectable stage III non‐small‐cell lung cancer based on the results of the PACIFIC trial …

[HTML][HTML] Outcomes with durvalumab by tumour PD-L1 expression in unresectable, stage III non-small-cell lung cancer in the PACIFIC trial

L Paz-Ares, A Spira, D Raben, D Planchard, BC Cho… - Annals of …, 2020 - Elsevier
Background In the PACIFIC trial, durvalumab significantly improved progression-free and
overall survival (PFS/OS) versus placebo, with manageable safety, in unresectable, stage III …

Patients with unresectable stage III non-small cell lung cancer eligible to receive consolidation therapy with durvalumab in clinical practice based on PACIFIC study …

T Sakaguchi, K Ito, K Furuhashi, Y Nakamura… - Respiratory …, 2019 - Elsevier
Background Compared to a placebo, durvalumab has been reported to significantly prolong
progression-free and overall survival in patients with stage III unresectable non-small cell …

Durvalumab real-world treatment patterns and outcomes in patients with stage III non-small-cell lung cancer treated in a US community setting

D Waterhouse, C Yong, A Frankart, L Brannman… - Future …, 2023 - Taylor & Francis
Background: For eligible patients with unresectable stage III non-small-cell lung cancer,
durvalumab consolidation therapy following chemoradiotherapy is the standard of care …

Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study

MC Garassino, BC Cho, JH Kim, J Mazières… - The Lancet …, 2018 - thelancet.com
Background Immune checkpoint inhibitors are a new standard of care for patients with
advanced non-small-cell lung cancer (NSCLC) without EGFR tyrosine kinase or anaplastic …