[HTML][HTML] Maintenance pharmacotherapy of mild and moderate COPD: what is the evidence?

GT Ferguson - Respiratory medicine, 2011 - Elsevier
Chronic obstructive pulmonary disease (COPD) affects more than 24 million individuals in
the United States, although at least half of the cases are not diagnosed. Proactive diagnosis …

[HTML][HTML] What have we learned from observational studies and clinical trials of mild to moderate COPD?

M Barrecheguren, C González, M Miravitlles - Respiratory research, 2018 - Springer
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide. It is well established that patients with mild to moderate disease represent the …

Rationale for earlier treatment in COPD: a systematic review of published literature in mild-to-moderate COPD

F Maltais, N Dennis, CKN Chan - COPD: Journal of Chronic …, 2013 - Taylor & Francis
COPD is progressive and typically begins many years before a definite diagnosis is made.
As the rate of decline in lung function may be faster in the initial stages of the disease, early …

Treatment of COPD: from pharmacological to instrumental therapies

M Alifano, A Cuvelier, A Delage… - European …, 2010 - Eur Respiratory Soc
Treatment guidelines are mainly based on randomised clinical trials that include a small and
highly selected fraction of the COPD population [2]. Therefore, it is questionable as to …

Optimising pharmacological maintenance treatment for COPD in primary care

R Jones, A Østrem - Primary Care Respiratory Journal, 2011 - nature.com
Chronic obstructive pulmonary disease (COPD) is a multi-faceted disease that is a major
cause of morbidity and mortality worldwide, and is a significant burden in terms of healthcare …

COPD: providing the right treatment for the right patient at the right time

A Agusti, N Ambrosino, F Blackstock, J Bourbeau… - Respiratory …, 2023 - Elsevier
Preface Chronic Obstructive Pulmonary Disease (COPD) is a common disease associated
with significant morbidity and mortality that is both preventable and treatable. However, a …

[HTML][HTML] Weighing the evidence for pharmacological treatment interventions in mild COPD; a narrative perspective

D Singh, AD D'Urzo, JF Donohue, EM Kerwin - Respiratory research, 2019 - Springer
There is increasing focus on understanding the nature of chronic obstructive pulmonary
disease (COPD) during the earlier stages. Mild COPD (Global Initiative for Chronic …

COPD: early diagnosis and treatment to slow disease progression

T Welte, C Vogelmeier, A Papi - International journal of clinical …, 2015 - Wiley Online Library
Aims Chronic obstructive pulmonary disease (COPD) is usually a progressive condition.
Undiagnosed early‐stage disease, particularly in symptomatic patients, is likely to become …

Should mild COPD be treated? Evidence for early pharmacological intervention

AF Elbehairy, KA Webb, J Alberto Neder, DE O'Donnell - Drugs, 2013 - Springer
Chronic obstructive pulmonary disease (COPD) is a common and often progressive
inflammatory disease of the airways that is both preventable and treatable. It is well …

Pharmacological treatment of COPD: the devil is always in the detail

D Singh, PJ Barnes, R Stockley… - European …, 2018 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition with
considerable pathophysiological and clinical variability across patients [1]. For this reason …