[HTML][HTML] Hepatocytes infected with hepatitis C virus change immunological features in the liver microenvironment

SJ Park, YS Hahn - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infection is remarkably efficient in establishing viral persistence,
leading to the development of liver cirrhosis and hepatocellular carcinoma (HCC). Direct …

Immune responses in hepatitis C virus infection and mechanisms of hepatitis C virus persistence

K Hiroishi, T Ito, M Imawari - Journal of gastroenterology and …, 2008 - Wiley Online Library
Immune responses against hepatitis C virus (HCV) play a crucial role in the pathogenesis of
chronic hepatitis C. HCV infection often persists and leads to chronic hepatitis and …

Immunopathogenesis of hepatitis C virus infection: multifaceted strategies subverting innate and adaptive immunity

T Kanto, N Hayashi - Internal Medicine, 2006 - jstage.jst.go.jp
Hepatitis C virus (HCV) infection is one of the major causes of chronic liver disease
worldwide. The critical role of innate as well as adaptive immunity has been reported in HCV …

Hepatitis C virus-mediated modulation of cellular immunity

ED Brenndörfer, M Sällberg - Archivum immunologiae et therapiae …, 2012 - Springer
The hepatitis C virus (HCV) is a major cause of chronic liver disease globally. A chronic
infection can result in liver fibrosis, liver cirrhosis, hepatocellular carcinoma and liver failure …

Immunopathogenesis of hepatitis C virus infection

KM Chang - Clinics in liver disease, 2003 - liver.theclinics.com
Hepatitis C virus (HCV) is a highly mutable, hepatotropic RNA virus that causes acute and
chronic hepatitis, affecting over 3% of world population [1–8]. HCV infection frequently …

Liver abnormalities after elimination of HCV infection: persistent epigenetic and immunological perturbations post-cure

SJ Polyak, IN Crispe, TF Baumert - Pathogens, 2021 - mdpi.com
Chronic hepatitis C (CHC) is a major cause of hepatocellular carcinoma (HCC) worldwide.
While directly acting antiviral (DAA) drugs are now able to cure virtually all hepatitis C virus …

T cell responses in hepatitis C: the good, the bad and the unconventional

P Klenerman, R Thimme - Gut, 2012 - gut.bmj.com
Over recent years, it has become increasingly accepted that virus-specific CD4+ and CD8+
T cell responses play a major role in outcome and pathogenesis of hepatitis C virus (HCV) …

Immunological mechanisms for hepatocellular carcinoma risk after direct-acting antiviral treatment of hepatitis C virus infection

PS Sung, EC Shin - Journal of clinical medicine, 2021 - mdpi.com
Direct-acting antiviral agents (DAAs) that allow for rapid clearance of hepatitis C virus (HCV)
may evoke immunological changes. Some cases of rapid de novo hepatocellular carcinoma …

Immunopathogenesis in hepatitis C virus cirrhosis

U Spengler, J Nattermann - Clinical science, 2007 - portlandpress.com
HCV (hepatitis C virus) has a high propensity to persist and to cause chronic hepatitis C,
eventually leading to cirrhosis. Since HCV itself is not cytopathic, liver damage in chronic …

[HTML][HTML] Hepatitis C virus infection: establishment of chronicity and liver disease progression

YC Kwon, RB Ray, R Ray - EXCLI journal, 2014 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) often causes persistent infection, and is an important factor in the
etiology of fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). There are no preventive …