Abstract Silent information regulator 1 (SIRT1), a highly conserved NAD+-dependent
deacetylase, is a cellular regulator that has received extensive attention in recent years and …

Abstract Sirtuins or Sir (Silent information regulator) are NAD+-dependent enzymes playing
an important part in the pathogenesis and treatment of various disorders. They have …

SIRT1 protein, a member of Silent Information Regulator 2 (Sir2) protein family, have gained
considerable attention as epigenetic regulators for a great area in the human physiology …

Abstract Sirtuin 1 (SIRT1) is the most conserved mammalian NAD+-dependent protein
deacetylase that has emerged as a key metabolic sensor in various metabolic tissues. In …

Sirt1 (member of the sirtuin family) is a nicotinamide adenosine dinucleotide (NAD)-
dependent deacetylase that removes acetyl groups from various proteins. Sirt1 performs a …

Silent information regulator two homologue one (SIRT1) is the most widely studied member
of the sirtuin family related to histone deacetylases class III super-family using nicotinamide …

The NAD+-dependent protein deacetylase SIRT1 regulates energy metabolism, responses
to stress, and aging by deacetylating many different proteins, including histones and …

Abstract Silent information regulator 1 (SIRT1) is a ubiquitously expressed protein and has
an intricate role in the pathology, progression, and treatment of several diseases. SIRT1 is a …

As an important NAD+-dependent enzyme, SIRT6 has received significant attention since its
discovery. In view of observations that SIRT6-deficient animals exhibit genomic instability …

SIRT1, an NAD+-dependent deacetylase, has been described in the literature as a major
player in the regulation of cellular stress responses. Its expression has been shown to be …