Genomic instability and inflammation are considered to be two enabling characteristics that
support cancer development and progression. G-quadruplex structure is a key element that …

G-quadruplex, a unique secondary structure in nucleic acids found throughout human
genome elicited widespread interest in the field of therapeutic research. Being present in …

Nucleic acid sequences able to adopt a G-quadruplex conformation are overrepresented
within the human genome. This evidence strongly suggests that these genomic regions …

G-quadruplex is a special secondary structure of nucleic acids in guanine-rich sequences of
genome. G-quadruplexes have been proved to be involved in the regulation of replication …

G‐Quadruplex, a unique secondary structure in nucleic acids found throughout human
genome, elicited widespread interest in the field of therapeutic research. Being present in …

G-quadruplexes are four-stranded DNA structures that are over-represented in gene
promoter regions and are viewed as emerging therapeutic targets in oncology, as …

Non-canonical, four-stranded nucleic acids secondary structures are present within
regulatory regions in the human genome and transcriptome. To date, these quadruplex …

Abstract G-quadruplex (G4) is a non-canonical nucleic acid structure formed in guanine-rich
DNA or RNA. G4s are formed not only in vitro but also in vivo and are attracting considerable …

Simple Summary Four-stranded nucleic acid secondary structures (quadruplexes) including
DNA G-quadruplexes, RNA G-quadruplexes and i-Motifs display key regulatory functions in …

Background There are some problems in the clinical diagnosis of colorectal cancer (CRC),
such as the difficulty in saving samples, so it is the most popular research work to develop a …