The pathophysiology of acute renal failure (ARF) in sepsis is only partly understood. In
several animal models of septic ARF, no profound tissue hypoxia or decrease in …

The kidney is comprised of heterogeneous cell populations that function together to perform
a number of tightly controlled, complex and interdependent processes. Renal endothelial …

Mortality in acute kidney injury (AKI) patients remains very high, although very important
advances in understanding the pathophysiology and in diagnosis and supportive care have …

AKI is a common complication of sepsis and is significantly associated with mortality. Sepsis
accounts for more than 50% of the cases of AKI, with a mortality rate of up to 40%. The …

The pathophysiology of sepsis-induced acute kidney injury remains poorly understood. As
changes in renal perfusion and oxygenation have been shown, we aimed to study the short …

Acute kidney injury is a frequent complication in the intensive care unit that is associated
with increased mortality and morbidity. Traditional models consider reductions of global …

Acute kidney injury (AKI), or acute renal failure, is associated with hospital stays, increased
economic costs, and significant mortality, particularly in the context of critically ill patients in …

Acute kidney injury (AKI) is a serious condition that affects many ICU patients. The most
common causes of AKI in ICU are severe sepsis and septic shock. The mortality of AKI in …

Ischemic acute renal failure: An inflammatory disease? Inflammation plays a major role in
the pathophysiology of acute renal failure resulting from ischemia. In this review, we discuss …

Objectives: To determine whether there is a decrease in renal cortical or medullary perfusion
and oxygenation in a conscious large animal model of hyperdynamic septic shock with …