Chronic myeloid leukemia and pregnancy: when dreams meet reality. State of the art, management and outcome of 41 cases, nilotinib placental transfer

E Abruzzese, S Aureli, F Bondanini… - Journal of Clinical …, 2022 - mdpi.com
The overwhelming success of tyrosine kinase inhibitor (TKI) therapy in chronic myeloid
leukemia (CML) patients has opened a discussion among medical practitioners and the lay …

Two successful pregnancies in a woman with chronic myeloid leukemia exposed to nilotinib during the first trimester of her second pregnancy: case study

M Conchon, SS Sanabani, I Bendit, FM Santos… - Journal of Hematology & …, 2009 - Springer
The occurrence of chronic myeloid leukemia in pregnancy is rare and its management
poses a clinical challenge for physicians treating these patients. We report a 30-year-old …

[HTML][HTML] GIMEMA registry of conception/pregnancy in adult patients diagnosed with chronic myeloid leukemia (CML) treated with tyrosine kinase inhibitors (TKIs)

E Abruzzese, AR Scortechini, G Gugliotta, I Pierri… - Blood, 2014 - Elsevier
The management of patients with chronic myeloid leukemia (CML) during pregnancy is a
matter of continuous debate. The introduction of the tyrosin kinase inhibitors (TKIs) in clinical …

[HTML][HTML] Management of chronic myeloid leukemia (CML) during pregnancy among patients (pts) treated with a tyrosine kinase inhibitor (TKI): a single-center …

R Assi, HM Kantarjian, MJ Keating, N Pemmaraju… - Blood, 2017 - Elsevier
Background: Exposure to TKI has teratogenic effects in animal studies and humans. CML is
being identified in younger patients who need to continue treatment for long periods of time …

Managing pregnancy in chronic myeloid leukemia

R Palani, D Milojkovic, JF Apperley - Chronic myeloid leukemia, 2016 - Springer
The success of tyrosine kinase inhibitors (TKIs) in the treatment of chronic myeloid
leukaemia (CML) has resulted in a return to a normal life expectancy for the majority of …

Management of pregnant chronic myeloid leukemia patients

E Abruzzese, MM Trawinska, P de Fabritiis… - Expert Review of …, 2016 - Taylor & Francis
Introduction: Since the introduction of tyrosine kinase inhibitors (TKIs) therapy, chronic
myeloid leukemia (CML), has moved from a fatal illness to a manageable disease with a …

Family planning and pregnancy in patients with chronic myeloid leukemia

E Berman - Current Hematologic Malignancy Reports, 2023 - Springer
Abstract Purpose of Review The goal of this review is to summarize what is known about
pregnancy in women with chronic myeloid leukemia (CML): there are very few guidelines …

Management of chronic myeloid leukemia during pregnancy among patients treated with a tyrosine kinase inhibitor: a single-Center experience

R Assi, H Kantarjian, M Keating… - Leukemia & …, 2021 - Taylor & Francis
Tyrosine kinase inhibitors (TKIs) are teratogenic. Chronic myeloid leukemia (CML) is
increasingly identified in younger patients who wish to conceive, the management of CML …

Fertility and pregnancy in chronic myeloid leukemia: real-world experience from an Indian tertiary care institution

PS Malik, RK Sahoo, S Sharawat, M Singh, V Garg… - Annals of …, 2023 - Springer
Chronic myeloid leukemia (CML) management during pregnancy is challenging. In this
retrospective study, hospital records of CML patients treated between 2000 and 2021 were …

Loss of Pregnancy in a Patient with Chronic Myeloid Leukemia During Treatment with Nilotinib.

J Arnall, B Muluneh - Journal of Hematology Oncology …, 2016 - search.ebscohost.com
Background: Treatment of chronic myeloid leukemia (CML) with imatinib and more recent
therapeutic agents has brought a drastic change in the course of this malignancy. Some …