Early-life adverse events or childhood adversities (CAs) are stressors and harmful
experiences severely impacting on a child's wellbeing and development. Examples of CAs …

Studies have reported an association between adverse childhood experiences (ACEs) and
the clinical outcomes of bipolar disorder (BD). However, these studies have several …

Abstract Background Risk for Bipolar disorder (BD) is increased among individuals with
family history or subthreshold mood symptoms. However, the brain structural developments …

Adverse childhood experiences (ACEs) negatively affect the function and structure of
emotion brain circuits, increasing the risk of various psychiatric disorders. It is unclear if …

Objective: Neuroimaging studies show structural brain abnormalities in bipolar patients.
Some of the abnormalities may represent biological risk factors conveying vulnerability for …

Background: Although early interventions in individuals with bipolar disorder may reduce the
associated personal and economic burden, the neurobiologic markers of enhanced risk are …

Childhood maltreatment is associated with adverse effects on the brain, and an increased
risk for psychopathology, including mood and substance use disorders. Individuals vary on …

Background: To date, many studies have attempted to show a relationship between
potentially harmful experiences in childhood and gray matter volume (GMV) in specific brain …

Introduction: Children and adolescents with bipolar disorder often present with higher rates
of mixed episodes, rapid cycling, and co-occurring attention-deficit/hyperactivity disorder …

Although neurobiological mechanisms of bipolar disorder (BD) are still unclear, neural
models of the disease have recently been conceptualised thanks to neuroimaging. Indeed …