[HTML][HTML] Promising therapeutic targets for treatment of rheumatoid arthritis

J Huang, X Fu, X Chen, Z Li, Y Huang… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic poly-articular chronic autoimmune joint disease that
mainly damages the hands and feet, which affects 0.5% to 1.0% of the population …

[HTML][HTML] Signaling pathways in rheumatoid arthritis: implications for targeted therapy

Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

[HTML][HTML] Recent advances in understanding the pathogenesis of rheumatoid arthritis: new treatment strategies

AL Mueller, Z Payandeh, N Mohammadkhani… - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

[HTML][HTML] Anti-rheumatoid drugs advancements: New insights into the molecular treatment of rheumatoid arthritis

RB Mrid, N Bouchmaa, H Ainani, R El Fatimy… - Biomedicine & …, 2022 - Elsevier
Rheumatoid arthritis (RA) is one of more than 100 types of arthritis. This chronic autoimmune
disorder affects the lining of synovial joints in about 0.5% of people and may induce severe …

[HTML][HTML] Immunopathogenic mechanisms and novel immune-modulated therapies in rheumatoid arthritis

SJ Chen, GJ Lin, JW Chen, KC Wang, CH Tien… - International Journal of …, 2019 - mdpi.com
Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disease of unknown
etiology. It is characterized by the presence of rheumatoid factor and anticitrullinated peptide …

Recent advances on signaling pathways and their inhibitors in rheumatoid arthritis

S Liu, H Ma, H Zhang, C Deng, P Xin - Clinical Immunology, 2021 - Elsevier
Rheumatoid arthritis (RA) is characterized by systemic synovitis leading to joint destruction
in which imbalances in pro-inflammatory and anti-inflammatory cytokines promote the …

[PDF][PDF] One year in review 2020: pathogenesis of rheumatoid arthritis

D Giannini, M Antonucci, F Petrelli, S Bilia… - Clin Exp …, 2020 - clinexprheumatol.org
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease influenced by both
genetic, epigenetic and environmental factors. The discovery of new gene polymorphisms …

[PDF][PDF] One year in review 2019: pathogenesis of rheumatoid arthritis

C Croia, R Bursi, D Sutera, F Petrelli… - Clin Exp …, 2019 - clinexprheumatol.org
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease influenced by both
genetic and environmental factors. Over the last few years, particular attention has been …

[HTML][HTML] The therapeutic landscape of rheumatoid arthritis: current state and future directions

S Shams, JM Martinez, JRD Dawson, J Flores… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a debilitating autoimmune disease with grave physical,
emotional and socioeconomic consequences. Despite advances in targeted biologic and …

[PDF][PDF] Pathogenesis of rheumatoid arthritis: One year in review 2023

FM Mariani, I Martelli, F Pistone… - Clin. Exp …, 2023 - clinexprheumatol.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by local and
systemic inflammation. The complex interplay between immune cells and soluble mediators …