In vivo imaging of canine lung deformation: effects of posture, pneumonectomy, and inhaled erythropoietin

C Yilmaz, DM Dane, NJ Tustison… - Journal of applied …, 2020 - journals.physiology.org
Mechanical stresses on the lung impose the major stimuli for developmental and
compensatory lung growth and remodeling. We used computed tomography (CT) to …

Separating in vivo mechanical stimuli for postpneumonectomy compensation: imaging and ultrastructural assessment

P Ravikumar, C Yilmaz, DJ Bellotto… - Journal of applied …, 2013 - journals.physiology.org
Following right pneumonectomy (PNX), the remaining lung expands and its perfusion more
than doubles. Tissue and microvascular mechanical stresses are putative stimuli for …

Progressive adaptation in regional parenchyma mechanics following extensive lung resection assessed by functional computed tomography

C Yilmaz, NJ Tustison, DM Dane… - Journal of applied …, 2011 - journals.physiology.org
In adult canines following major lung resection, the remaining lobes expand asymmetrically,
associated with alveolar tissue regrowth, remodeling, and progressive functional …

Mapping cyclic stretch in the postpneumonectomy murine lung

N Filipovic, BC Gibney, M Kojic… - Journal of applied …, 2013 - journals.physiology.org
In many mammalian species, the removal of one lung [pneumonectomy (PNX)] is associated
with the compensatory growth of the remaining lung. To investigate the hypothesis that …

Noninvasive quantification of heterogeneous lung growth following extensive lung resection by high-resolution computed tomography

C Yilmaz, P Ravikumar, DM Dane… - Journal of applied …, 2009 - journals.physiology.org
To quantify the in vivo magnitude and distribution of regional compensatory lung growth
following extensive lung resection, we performed high-resolution computed tomography at …

Effect of body orientation on regional lung expansion: a computed tomographic approach

EA Hoffman - Journal of Applied Physiology, 1985 - journals.physiology.org
The Dynamic Spatial Reconstructor (DSR) was used to study in vivo lung geometry and
function. By replacing the lungs of three dogs with potato flakes and ping-pong balls of …

[HTML][HTML] Distribution and magnitude of regional volumetric lung strain and its modification by PEEP in healthy anesthetized and mechanically ventilated dogs

J Araos, P Cruces, M Martin-Flores, P Donati… - Frontiers in Veterinary …, 2022 - frontiersin.org
The present study describes the magnitude and spatial distribution of lung strain in healthy
anesthetized, mechanically ventilated dogs with and without positive end-expiratory …

Perfusion-related stimuli for compensatory lung growth following pneumonectomy

DM Dane, C Yilmaz, D Gyawali, R Iyer… - Journal of applied …, 2016 - journals.physiology.org
Following pneumonectomy (PNX), two separate mechanical forces act on the remaining
lung: parenchymal stress caused by lung expansion, and microvascular distension and …

Computational analysis of lung deformation after murine pneumonectomy

N Filipovic, BC Gibney, D Nikolic… - Computer methods in …, 2014 - Taylor & Francis
In many mammalian species, the removal of one lung (pneumonectomy) is associated with
the compensatory growth of the remaining lung. To investigate the hypothesis that …

Developmental signals do not further accentuate nonuniform postpneumonectomy compensatory lung growth

P Ravikumar, C Yilmaz, DM Dane… - Journal of applied …, 2007 - journals.physiology.org
Mechanical forces imposed on lung tissue constitute major stimuli for normal lung
development and postpneumonectomy (PNX) compensatory growth and remodeling …