Some metabolic pathways involve two different cell components, for instance, cytosol and
mitochondria, with metabolites traffic occurring from cytosol to mitochondria and vice versa …

Lactate has long been considered a cellular waste product. However, we found that as
extracellular lactate accumulates, it also enters the mitochondrial matrix and stimulates …

Publisher Summary This chapter discusses the metabolite carriers in mitochondria. For
many metabolic processes in the cell a concerted function of both the cytosolic and the …

The yeast Saccharomyces cerevisiae is one of the most widely used model organisms for
investigating various aspects of basic cellular functions that are conserved in human cells …

Publisher Summary This chapter deals with the mitochondrial ion transport. As many
metabolic processes in the cell require the participation of both intra-and extra-mitochondrial …

Hepatic gluconeogenesis is crucial for maintaining blood glucose during starvation, and a
major contributor for hyperglycemia. Cellular redox state is related to mitochondrial biology …

Since mitochondria are closed spaces in the cell, metabolite traffic across the mitochondrial
membrane is needed to accomplish energy metabolism. The mitochondrial carriers play this …

The mitochondrial carrier system (MCS) transports small molecules between mitochondria
and the cytoplasm. It is integral to the core mitochondrial function to regulate cellular …

In the light of the occurrence of l-lactate dehydrogenase inside the mitochondrial matrix, we
looked at whether isolated rat liver mitochondria can take up and metabolize l-lactate, and …

According to current concepts, the membrane of rat liver mitochondria is relatively
impermeable to oxalacetate, and carbon or hydrogen equivalents for gluconeogenesis are …