The complexities and challenges of preventing and treating nontuberculous mycobacterial diseases

SL Baldwin, SE Larsen, D Ordway… - PLoS neglected …, 2019 - journals.plos.org
Seemingly innocuous nontuberculous mycobacteria (NTM) species, classified by their slow
or rapid growth rates, can cause a wide range of illnesses, from skin ulceration to severe …

Advancing translational science for pulmonary nontuberculous mycobacterial infections. A road map for research

S Daniel-Wayman, G Abate, DL Barber… - American journal of …, 2019 - atsjournals.org
Nontuberculous mycobacterial pulmonary disease (NTM PD) may be chronic, requiring
lengthy and complex regimens over many months to years. After treatment, patients are …

[HTML][HTML] Leveraging advances in tuberculosis diagnosis and treatment to address nontuberculous mycobacterial disease

RM Raju, SM Raju, Y Zhao, EJ Rubin - Emerging infectious …, 2016 - ncbi.nlm.nih.gov
The nontuberculous mycobacteria (NTM), defined as any mycobacterial pathogen other than
Mycobacterium tuberculosis or Mycobacterium leprae, are a diverse group of pathogens that …

Non-tuberculous mycobacteria: Molecular and physiological bases of virulence and adaptation to ecological niches

AC Pereira, B Ramos, AC Reis, MV Cunha - Microorganisms, 2020 - mdpi.com
Non-tuberculous mycobacteria (NTM) are paradigmatic colonizers of the total environment,
circulating at the interfaces of the atmosphere, lithosphere, hydrosphere, biosphere, and …

The rise of non-tuberculosis mycobacterial lung disease

CN Ratnatunga, VP Lutzky, A Kupz, DL Doolan… - Frontiers in …, 2020 - frontiersin.org
The incidence and number of deaths from non-tuberculous mycobacterial (NTM) disease
have been steadily increasing globally. These lesser known “cousins” of Mycobacterium …

Challenges of NTM drug development

JO Falkinham III - Frontiers in microbiology, 2018 - frontiersin.org
Discovery and development of antibiotics active against the environmental opportunistic non-
tuberculous mycobacteria (NTM) have been retarded by innate antibiotic-resistance of NTM …

Skin and soft tissue infections due to nontuberculous mycobacteria

EA Misch, C Saddler, JM Davis - Current infectious disease reports, 2018 - Springer
Abstract Purpose of Review This review describes recent trends in the epidemiology of
nontuberculous mycobacteria (NTM), emerging pathogens, new insights into NTM …

Challenges facing the drug discovery pipeline for non-tuberculous mycobacteria

I Soni, MA De Groote, A Dasgupta… - Journal of Medical …, 2016 - microbiologyresearch.org
Non-tuberculous mycobacteria (NTM) infections are increasingly being reported worldwide.
They are a major concern for healthcare professionals for multiple reasons, ranging from the …

[HTML][HTML] Non-tuberculous mycobacterial infections—a neglected and emerging problem

I Ahmed, S Tiberi, J Farooqi, K Jabeen… - International Journal of …, 2020 - Elsevier
Non-tuberculous mycobacteria (NTM) are ubiquitous dwellers of environmental niches and
are an established cause of natural and nosocomial infections. The incidence of NTM …

[HTML][HTML] Nontuberculous mycobacteria in humans, animals, and water in Zambia: a systematic review

M Zulu, N Monde, P Nkhoma, S Malama… - Frontiers in Tropical …, 2021 - frontiersin.org
Nontuberculous mycobacteria (NTM) are environmental opportunistic pathogens of humans
and animals that are emerging with a serious public health impact particularly in individuals …