The RNA metabolism involves different steps from transcription to translation and decay of
messenger RNAs (mRNAs), and those different layers are each regulated and …

Poly (A) tails protect RNAs from degradation and their deadenylation rates determine RNA
stability. Although poly (A) tails are generated in the nucleus, deadenylation of tails has …

In eukaryotes, poly (A) tails are present on almost every mRNA. Early experiments led to the
hypothesis that poly (A) tails and the cytoplasmic polyadenylate-binding protein (PABPC) …

Beyond the well-known function of poly (A) tail length in mRNA stability, recent years have
witnessed an explosion of information about how changes in tail length and the selection of …

In eukaryotes, mRNA metabolism requires a sophisticated signaling system. Recent studies
have suggested that polyadenylate tail may play a vital role in such a system. The poly (A) …

Deadenylation of mRNAs is generally associated with translational inhibition and mRNA
decay. A study now reports that, unexpectedly, highly expressed genes tend to have shorter …

Poly (A) tails are non-templated additions of adenosines at the 3′ ends of most eukaryotic
mRNAs. In the nucleus, these RNAs are co-transcriptionally cleaved at a poly (A) site and …

Poly (A) tails are important elements in mRNA translation and stability, although recent
genome-wide studies have concluded that poly (A) tail length is generally not associated …

Nearly all eukaryotic mRNAs terminate in a poly (A) tail that serves important roles in mRNA
utilization. In the cytoplasm, the poly (A) tail promotes both mRNA stability and translation …

The 3′ poly (A) tail has important roles throughout the eukaryotic mRNA life cycle. A
characteristic aspect of poly (A) tail function is furthermore that it can be modulated by …