Spirulina maxima Extract Prevents Neurotoxicity via Promoting Activation of BDNF/CREB Signaling Pathways in Neuronal Cells and Mice

EJ Koh, YJ Seo, J Choi, HY Lee, DH Kang, KJ Kim… - Molecules, 2017 - mdpi.com
Spirulina maxima is a microalgae which contains flavonoids and other polyphenols.
Although Spirulina maxima 70% ethanol extract (SM70EE) has diverse beneficial effects, its …

Spirulina maxima Extract Ameliorates Learning and Memory Impairments via Inhibiting GSK-3β Phosphorylation Induced by Intracerebroventricular Injection of …

EJ Koh, KJ Kim, JH Song, J Choi, HY Lee… - International Journal of …, 2017 - mdpi.com
Spirulina maxima, a microalga containing high levels of protein and many polyphenols,
including chlorophyll a and C-phycocyanin, has antioxidant and anti-inflammatory …

The Protein-Rich Fraction from Spirulina platensis Exerts Neuroprotection in Hemiparkinsonian Rats by Decreasing Brain Inflammatory-Related Enzymes and Glial …

MJP Lopes, GA Delmondes, GML Leite… - Journal of Medicinal …, 2022 - liebertpub.com
Spirulina platensis is a cyanobacterium with high protein content and presenting
neuroprotective effects. Now, we studied a protein-enriched fraction (SPF), on behavior …

Spirulina maxima extract prevents cell death through BDNF activation against amyloid beta 1-42 (Aβ1-42) induced neurotoxicity in PC12 cells

EJ Koh, KJ Kim, J Choi, DH Kang, BY Lee - Neuroscience letters, 2018 - Elsevier
Spirulina maxima is a blue-green micro alga that contains abundant amounts of proteins (60–
70%), vitamins, chlorophyll a, and C-phycocyanin (C-PC). It has been shown to reduce …

Spirulina platensis Suppressed iNOS and Proinflammatory Cytokines in Lipopolysaccharide-Induced BV2 Microglia

EL Ngu, CY Tan, NJY Lai, KH Wong, SH Lim, LC Ming… - Metabolites, 2022 - mdpi.com
The disease burden of neurodegenerative diseases is on the rise due to the aging
population, and neuroinflammation is one of the underlying causes. Spirulina platensis is a …

[HTML][HTML] Protective effect of water extracted Spirulina maxima on glutamate-induced neuronal cell death in mouse hippocampal HT22 cell

HY Lee, GH Ryu, WY Choi, WS Yang… - Pharmacognosy …, 2018 - ncbi.nlm.nih.gov
Materials and Methods: S. maxima was extracted in water and contain of phycocyanin was
identified by high-performance liquid chromatography. Cell viability test was performed with …

Synergistic Neuroprotective Effect of Schisandra chinensis and Ribes fasciculatum on Neuronal Cell Death and Scopolamine-Induced Cognitive Impairment in Rats

E Park, MJ Ryu, NK Kim, MH Bae, Y Seo, J Kim… - International journal of …, 2019 - mdpi.com
Mild cognitive impairment (MCI) is considered as a transitional stage between aging and
Alzheimer's disease. In the present study, we examined the protective effect of Schisandra …

Therapeutic Effects of Spirulina platensis Against Adolescent Stress-Induced Oxidative Stress, Brain-Derived Neurotrophic Factor Alterations and Morphological …

N Moradi-Kor, A Ghanbari, H Rashidipour… - Journal of …, 2020 - Taylor & Francis
Objective The amygdala structural and functional abnormalities have been implicated in
numerous neuropsychiatric and neurodevelopmental disorders. Given the important role of …

Spirulina platensis reduces the schizophrenic-like symptoms in rat model by restoring altered APO-E and RTN-4 protein expression in prefrontal cortex

S Haider, S Shahzad, Z Batool, S Sadir, L Liaquat… - Life Sciences, 2021 - Elsevier
Aims Schizophrenia (SZ) is recognized as a neuropsychiatric disorder in humans with
accelerated mortality and profound morbidity followed with impairments in social as well as …

[HTML][HTML] Fisetin protects against rotenone-induced neurotoxicity through signaling pathway

M Rajendran, R Ramachandran - Frontiers in Bioscience-Elite, 2019 - imrpress.com
The present study was designed to evaluate the protective effect of fisetin against rotenone
induced toxicity in SH-SY5Y neuroblastoma cellular modelof Parkinson's disease (PD). SH …