Effects of the prone position on regional neutrophilic lung inflammation according to 18F-FDG pet in an experimental ventilator-induced lung injury model

S Nakahashi, H Imai, N Shimojo, Y Magata, T Einama… - Shock, 2022 - journals.lww.com
Ventilator-induced lung injury (VILI) can be life-threatening and it is important to prevent the
development of VILI. It remains unclear whether the prone position affects neutrophilic …

Prone position decreases acute lung inflammation measured by [11C](R)-PK11195 positron emission tomography in experimental acute respiratory distress …

F Dhelft, S Lancelot, W Mouton… - Journal of Applied …, 2023 - journals.physiology.org
Whether prone positioning (PP) modulates acute lung inflammation by the modulation of
biomechanical forces of ventilator-induced lung injuries (VILIs) remains unclear. We aimed …

Low Positive End-Expiratory Pressure Ventilation Increases Mechanical Power and Pulmonary Neutrophilic Inflammation in an Experimental Model of Moderate to …

M Scharffenberg, R Huhle, J Wittenstein… - D15. GOOD, BETTER …, 2022 - atsjournals.org
Rationale: Mechanical ventilation (MV) may initiate or worsen lung injury, known as
ventilator-induced lung injury (VILI). While different VILI mechanisms have been identified …

Body position does not influence the location of ventilator-induced lung injury

M Nishimura, O Honda, N Tomiyama, T Johkoh… - Intensive care …, 2000 - Springer
Objective: To ascertain whether the locations of ventilator-induced lung injury (VILI) are
influenced by body position. Design: Randomized prospective short-term study. Setting …

Prone position prevents regional alveolar hyperinflation and mechanical stress and strain in mild experimental acute lung injury

MCE Santana, CSNB Garcia, DG Xisto… - Respiratory physiology …, 2009 - Elsevier
Prone position may delay the development of ventilator-induced lung injury (VILI), but the
mechanisms require better elucidation. In experimental mild acute lung injury (ALI), arterial …

Early inflammation mainly affects normally and poorly aerated lung in experimental ventilator-induced lung injury

JB Borges, ELV Costa, F Suarez-Sipmann… - Critical care …, 2014 - journals.lww.com
Objective: The common denominator in most forms of ventilator-induced lung injury is an
intense inflammatory response mediated by neutrophils. PET with [18 F] fluoro-2-deoxy-D …

Mechanical power correlates with lung inflammation assessed by positron-emission tomography in experimental acute lung injury in pigs

M Scharffenberg, J Wittenstein, X Ran, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
Background: Mechanical ventilation (MV) may initiate or worsen lung injury, so-called
ventilator-induced lung injury (VILI). Although different mechanisms of VILI have been …

Regional gas exchange and cellular metabolic activity in ventilator-induced lung injury

G Musch, JG Venegas, G Bellani, T Winkler… - The Journal of the …, 2007 - pubs.asahq.org
Background Alveolar overdistension and repetitive derecruitment-recruitment contribute to
ventilator-induced lung injury (VILI). The authors investigated (1) whether inflammatory cell …

Regional Lung Inflammation And Ventilator-Induced Lung Injury Monitored By Positron Emission Tomography

JB Borges, ELV Costa, E Maripuu… - B95. DIAGNOSING …, 2010 - atsjournals.org
Representative images of cross-registered computed tomography (CT) and [18F]-fluoro-2-
deoxy-D-glucose (18FDG) positron emission tomography from a porcine acute respiratory …

Lung Metabolic Changes Precede Lung Structural Changes During Acute Lung Injury Produced By Endotoxin And Mechanical Ventilation

TJ Wellman, N de Prost, T Winkler, G Musch… - … INJURY: BENCH TO …, 2012 - atsjournals.org
(VILI), inflammation is triggered by the presence of injurious mechanisms, which also cause
structural changes in the lung. Whether such inflammation precedes and may play a role in …