Objective To investigate the effects and mechanism of prone ventilation in rats with
lipopolysaccharide (LPS)-induced extra pulmonary acute lung injury (ALI). Methods Thirty …

The use of positive pressure mechanical ventilation can cause ventilator-induced lung injury
(VILI). We hypothesized that hyperoxia in combination with large tidal volumes (Vt) would …

Positive pressure ventilation is commonly applied in patients undergoing general
anesthesia or requiring ventilatory support due to acute respiratory failure to assure …

Understanding how the mechanisms of ventilator-induced lung injury (VILI), namely
atelectrauma and volutrauma, contribute to the failure of the blood-gas barrier and …

Introduction Ventilator-induced lung injury (VILI) impacts clinical outcomes in acute
respiratory distress syndrome (ARDS), which is characterized by neutrophil-mediated …

Patients undergoing mechanical ventilation in intensive care units (ICUs) may develop
ventilator-induced lung injury (VILI). Beside the high tidal volume (Vt) and plateau pressure …

For patients with acute lung injury, positive pressure mechanical ventilation is life saving.
However, considerable experimental and clinical data have demonstrated that how …

The mechanism of oxygenation improvement after recruitment manoeuvres or prone
positioning in acute lung injury or acute respiratory distress syndrome is still unclear. We …

Background To examine whether acute lung injury from direct and indirect origins differ in
susceptibility to ventilator-induced lung injury (VILI) and resultant systemic inflammatory …

Supportive mechanical ventilation is a necessary lifesaving treatment for acute respiratory
distress syndrome (ARDS). This intervention often leads to injury exacerbation by ventilator …